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Microbial Natural Product Library

Catalog No. L6500
  Library Compound List   Excel SDF

Microscopic organisms, commonly known as microorganisms or microbes, are found all around us and even inside our bodies, including a massive range of organisms including bacteria, fungi, viruses, algae, archaea and protozoa. The vast majority of microbes on the earth pose no real threat to humans, plants or animals; in fact they actually work alongside humans to make world go round, aiding decomposition, decay and even helping us to digest our food. Microorganisms are renowned as a prolific source of natural products, making huge contribution to human health. The 1945 and 1952 Nobel Prizes in Physiology or Medicine were awarded for the discovery of penicillin and streptomycin, respectively. Six years later, the 2015 Nobel Prize in Physiology or Medicine was awarded to William C. Campbell and Satoshi Omura, and Youyou Tu for the discovery of avermectins and artemisinin, respectively, therapies that revolutionized the treatment of devastating parasite diseases. Among these four natural products awarded with Nobel Prizes, except for artemisinin, the other three all are microbial natural products. Streptomyces is the important source for natural medicines, the largest antibiotic-producing genus, producing antibacterial (vancomycin and daptomycin, etc.), antifungal (nystatin, amphotericin B, and natamycin), and antiparasitic drugs (Ivermectin), and also a wide range of other bioactive compounds used in other medical treatment, such as anti-cancer drugs (dactinomycin and bleomycin).

Microbial Natural Product Library is a unique collection of 560 microbial natural products covering various chemical structures, such as β-lactam, macrolides, aminoglycoside, polypeptides, Chloramphenicol, Tetracycline compounds, Anthraquinone, Benzene derivatives, quinone, Terpenoids, etc. This library can be used in rational drug design, virtual screening, and microbes classification, etc.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 560 microbial natural products for high throughput screening (HTS) and high content screening (HCS);
  • Targets include alpha-glucosidase, beta-lactamase, TNF-alpha, HDAC, PKC, HSP90, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L6500)

Publications Cited TargetMol Libraries

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Library Composition

Endogenous Metabolite (234)
Antibacterial (162)
Antibiotic (144)
Apoptosis (46)
Autophagy (37)
Antifungal (32)
ribosome (24)
DNA/RNA Synthesis (21)
Parasite (15)
Reactive Oxygen Species (11)
Antioxidant (10)
Influenza Virus (9)
Calcium Channel (8)
Phosphatase (7)
Ferroptosis (7)
Dehydrogenase (7)
PKC (7)
Nucleoside Antimetabolite/Analog (7)
NMDAR (6)
Topoisomerase (6)
iGluR (6)
Mitophagy (6)
Amino Acids and Derivatives (6)
GABA Receptor (6)
Anti-infection (5)
HIV Protease (5)
mTOR (5)
MMP (5)
COX (5)
Microtubule Associated (4)
Antifection (4)
Virus Protease (4)
NF-κB (4)
HSV (4)
Tyrosinase (4)
HMG-CoA Reductase (4)
Akt (4)
Caspase (4)
IL Receptor (3)
HDAC (3)
ROS (3)
Mitochondrial Metabolism (3)
Glucosidase (3)
Antiviral (3)
AChR (3)
Potassium Channel (3)
HSP (3)
Nrf2 (3)
NO Synthase (3)
Cell wall (3)
DHFR (3)
Chloride channel (3)
PI3K (3)
CAT (3)
TNF (2)
P450 (2)
GluR (2)
Adenosine Receptor (2)
HCV Protease (2)
DNA Alkylator/Crosslinker (2)
PKA (2)
Arginase (2)
HBV (2)
Carbonic Anhydrase (2)
Sodium Channel (2)
Tyrosine Kinases (2)
STAT (2)
GPCR19 (2)
p38 MAPK (2)
Adrenergic Receptor (2)
HIF/HIF Prolyl-Hydroxylase (2)
AMPK (2)
Immunology/Inflammation related (2)
Wnt/beta-catenin (2)
ATPase (2)
Aminopeptidase (2)
Drug Metabolite (2)
Integrin (1)
CRISPR/Cas9 (1)
Beta Amyloid (1)
GPR (1)
Casein Kinase (1)
Histone Methyltransferase (1)
Src (1)
FXR (1)
Phospholipase (1)
Neurokinin receptor (1)
Imidazoline Receptor (1)
NOD-like Receptor (NLR) (1)
AhR (1)
Proton pump (1)
NOD (1)
DNA Methyltransferase (1)
Syk (1)
Transaminase (1)
Dopamine Receptor (1)
Complement System (1)
Cannabinoid Receptor (1)
Hydrogenase (1)
Estrogen/progestogen Receptor (1)
FGFR (1)
PLK (1)
5-HT Receptor (1)
GluCls (1)
Prostaglandin Receptor (1)
Decarboxylase (1)
PDE (1)
DNA Alkylation (1)
ABC (1)
BCL (1)
MRP (1)
Estrogen Receptor/ERR (1)
DNA gyrase (1)
MT Receptor (1)
UGT (1)
Hedgehog/Smoothened (1)
IRE1 (1)
PPAR (1)
IAP (1)
Aryl Hydrocarbon Receptor (1)
ERK (1)
PARP (1)
Serine Protease (1)
JAK (1)
JNK (1)
transporter (1)
Lipid (1)
Sirtuin (1)
Free radical scavengers (1)
SARS-CoV (1)
Cysteine Protease (1)
Acyltransferase (1)
BCRP (1)
LTR (1)
ATP Citrate Lyase (1)
Histamine Receptor (1)
SGLT (1)
Interleukin (1)
aconitase (1)
NADPH (1)
Norepinephrine (1)
IGF-1R (1)
Lipase (1)
PTEN (1)
Proteasome (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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