Phenylpropanoids

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Phenylpropanoids are a large class of plant secondary metabolites derived from aromatic amino acids phenylalanine in most plants or tyrosine in partial monocots. It mainly includes flavonoids, monolignols, phenolic acids, stilbenes, and coumarins. Phenylpropanoids are widely distributed in the plant kingdom and play vital roles in plant development by acting as essential components of cell walls, protectants against high light and UV radiation, phytoalexins against herbivores and pathogens, floral pigments to mediate plant–pollinator interactions. In addition, phenylpropanoids possess diverse biological activities that are beneficial to human health.

Salviaflaside

TN1127178895-25-5

Salviaflaside is the main bioactive component of Prunella vulgaris and has antioxidant activity.

$100

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Isoforsythiaside

T3S10881357910-26-9

Isoforsythiaside has antioxidant, and antibacterial activities.

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L-DOPA

T084859-92-7

L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. It is a prodrug converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. In the brain, levodopa is decarboxylated to dopamine, stimulating dopaminergic receptors and compensating for depleted endogenous dopamine in Parkinson's disease. To ensure adequate concentrations reach the central nervous system, levodopa is administered with carbidopa, a decarboxylase inhibitor that does not cross the blood-brain barrier, reducing peripheral decarboxylation and increasing CNS dopamine delivery.

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(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid

TN707438489-76-8

(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid displays EC50 values of 73.5 μM against T. cruzi. trypomastigotes.

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Bimatoprost acid

T2093938344-08-0

Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP receptor on ovine luteal cells.

$135

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Methylsticin

TN2347495-85-2

Methysticin is a kavalactone isolated from the kava roots. Methylsticin (Methysticin) exhibit osteoclast formation inhibitory activity. It inhibits activation of NF-χB in lung adenocarcinoma tissue, activates Nrf2 in neurons and astroglia, decreases peak amplitude of voltage-gated Na+ channels in hippocampal neurons, and suppresses growth of Fusarium, Trichoderma, and Colletotrichum.

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4-Demethyldeoxypodophyllotoxin

T833213590-93-0

4-Demethyldeoxypodophyllotoxin, an aryl tetrahydronaphthalenyl lignan analog from the roots of Podophyllum peltatum, has anticancer activity and modulates the Chk-2 signaling pathway in MCF-7 breast cancer cells.

$122

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3-Feruloylquinic acid

TN12621899-29-2

3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.

$215

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Schizandrin A

T292661281-38-7

Schisandrin A, a primary active component extracted from the traditional Eastern medicine Schisandra chinensis, inhibits CYP3A activity, with an IC50 of 6.60 μM and a Ki of 5.83 μM.

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4-O-Cinnamoylquinic acid

TN66475509-70-6

4-O-Cinnamoylquinic acid is a small molecule compound extracted from the dried fruits of Casearia grewiifolia, which has an inhibitory effect on prostaglandins and inhibits the production of superoxide anions in human neutrophils.

$148

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Salvianolic acid D

TN2173142998-47-8

Salvianolic acid D ((R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid) and notoginseng triterpenes can promote EA-hy926 and expression of protein with protective effects on angiogenesis in EA-hy926 cells in vitro.

$180

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Verbasoside

TN522561548-34-3

Verbasoside (Decaffeoyl acteoside) is a phenylpropanoid isolated from the roots of Rehmannia glutinosa (Gaertn.) DC.

$257

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Lysergol

T15824602-85-7

Lysergol has been used as a hypotensive, psychotropic analgesic, and uterus- and intestine-stimulating drug. Lysergol is a clavinet alkaloid isolated from seeds of Ipomoea muricata and is a bioenhancer for the drugs and nutrients and has antibacterial act

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Shancigusin I

TN22061435488-35-9

Shancigusin I is a natural product from the tuber of Cremastra appendiculata.

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Maytansinol

T1601657103-68-1

Maytansinol (Ansamitocin P-0) inhibits microtubule assembly and causes microtubule disassembly in vitro.

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Regaloside C

TN6490117591-85-2

Regaloside C, a glycerol glucoside isolated from the Lilium genus, exhibits notable anti-inflammatory properties.

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Ethyl cinnamate

TN1624103-36-6

Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl cinnamate can inhibit the tonic contractions induced by high K+ and phenylephrine (PE) in a concentration-dependent manner, with respective IC50 values of 0.30 mM and 0.38 mM.

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(E)-3-(4-Methoxyphenyl)acrylic acid

T41095943-89-5

(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor with hepatoprotective, antiamnesic, and cognitive enhancement activities, and it can be used to lower blood pressure sugar.

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(E)-Cinnamamide

T1366922031-64-7

(E)-Cinnamamide (trans-Cinnamamide) is the less active isomer of Cinnamamide which is an effective non-lethal chemical repellent suitable for reducing avian pest damage.

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regaloside I

TN7117126239-78-9

Regaloside I is the monomeric component in lily. Regaloside I could be the main constituent in protecting human dermal fibroblasts from UVA-induced morphological changes [1].

$117

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Brandioside

TN1449133393-81-4

Brandioside (2'-Acetylpoliumoside), a phenylpropanoid glycoside obtainable from Callicarpa dichotoma Raeuschel, Verbenaceae, has antioxidant activity, attenuates glutamate-induced neurotoxicity, and can be used in the study of diabetes mellitus.

$193

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N1,N10-Bis(p-coumaroyl)spermidine

TN4621114916-05-1

N1,N10-Bis(p-coumaroyl)spermidine, which can be extracted from the herb of alfalfa, exhibits inhibitory effects on alpha-glucosidase.

$1,980

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3-Feruloyl-1-Sinapoyl sucrose

TN125198942-06-4

3-Feruloyl-1-Sinapoyl sucrose (Feruloyl Sinapoyl sucrose) is a glycoside isolated from Polygala chamaebuxus.

$320

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Erythro-Guaiacylglycerol beta-coniferyl ether

TN4003890317-92-7

Erythro-Guaiacylglycerol beta-coniferyl ether is a compound that can be extracted from the stems and leaves of mung beans and has inhibitory effects on alpha-glucosidase with an EC50 value of 18.71 μM.

$899

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Junipediol B 8-O-glucoside

TN4359188894-19-1

Junipediol B 8-O-glucoside is a phenylpropane extracted from the above-ground parts of Juniperus phoenicea.

$1,890

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alpha-(3,4-Dihydroxyphenyl)lactic acid

T349022681-72-7

Danshensu has antioxidant activity, can enhance HO-1 expression to suppress 6-OHDA-induced oxidative damage via PI3K Akt Nrf2 signaling pathways.

6-8 weeks

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Regaloside D

TN2140120601-66-3

Regaloside D is a natural product isolated from Lilium Longiflorum.

$400

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Lycibarbarphenylpropanoid B

TN81621988786-72-6

Lycibarbarphenylpropanoid B, a phenylpropanoid derived from wolfberry, demonstrates potent antioxidant properties. It has a notable oxygen radical absorbance capacity, reflected by an ORAC value of 3.18 μmol Trolox μmol (Trolox is a standard reference antioxidant, indicating that each μM of Lycibarbarphenylpropanoid B has antioxidant activity equivalent to 3.18 μM Trolox).

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Giraldoid B

TN81772300952-67-2

Giraldoid B, an active component isolated from Girald Daphne Bark, exhibits anti-inflammatory activity by inhibiting NO and TNF-α production in LPS-induced RAW264.7 cells.

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