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Martynoside
🥰Excellent
Catalog No. TMA0424Cas No. 67884-12-2
Martynoside is an active glycoside extracted from Rehmannia, with anti-estrogen, anticancer, cytotoxic, hematopoietic, antioxidant, and anti-metastatic properties. It increases IGFBP3 levels through the ER pathway.
Martynoside
🥰Excellent
Purity: 99.83%
Catalog No. TMA0424Cas No. 67884-12-2
Martynoside is an active glycoside extracted from Rehmannia, with anti-estrogen, anticancer, cytotoxic, hematopoietic, antioxidant, and anti-metastatic properties. It increases IGFBP3 levels through the ER pathway.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $137 | In Stock | |
| 5 mg | $389 | In Stock | |
| 10 mg | $625 | In Stock | |
| 25 mg | $972 | In Stock | |
| 50 mg | $1,280 | In Stock |
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Purity:99.83%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Martynoside is an active glycoside extracted from Rehmannia, with anti-estrogen, anticancer, cytotoxic, hematopoietic, antioxidant, and anti-metastatic properties. It increases IGFBP3 levels through the ER pathway. |
| In vitro | Martynoside attenuated 5-FU-induced cytotoxicity of bone marrow nucleated cells, increased the stability of RPL27A protein, and reduced RPL27A ubiquitination at lys92 (K92) and lys94 (K94) sites. [1] Martynoside(50 μg/ml) protects isolated bone marrow cells from 5-fluorouracil (5-FU) -induced cell death and inflammation by down-regulating the TNF signaling pathway. [2] |
| In vivo | Martynoside 10 mg/kg daily and receiving exercise for 5 weeks was found to have the potential to antagonize exercise anemia, and the mechanism of this effect may be related to preventing free radical damage to red blood cells. [3] |
| Molecular Weight | 652.64 |
| Formula | C31H40O15 |
| Cas No. | 67884-12-2 |
| Smiles | O([C@H]1[C@H](OC(/C=C/C2=CC(OC)=C(O)C=C2)=O)[C@@H](CO)O[C@@H](OCCC3=CC(O)=C(OC)C=C3)[C@@H]1O)[C@H]4[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4 |
| Relative Density. | 1.48g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 16 mg/mL (24.52 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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