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Neohesperidin

🥰Excellent
Catalog No. T2737Cas No. 13241-33-3
Alias NSC 31048, Hesperetin 7-O-neohesperidoside

Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.

Neohesperidin

Neohesperidin

🥰Excellent
Purity: 98.34%
Catalog No. T2737Alias NSC 31048, Hesperetin 7-O-neohesperidosideCas No. 13241-33-3
Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.
Pack SizePriceAvailabilityQuantity
50 mg$39In Stock
100 mg$51In Stock
500 mg$189In Stock
1 g$312In Stock
5 g$713In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:98.34%
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Product Introduction

Bioactivity
Description
Neohesperidin (NSC-31048) with antioxidant and neuroprotective properties. Unlike other citrus flavanones, it does not inhibit oral carcinogenesis in a rat model.
In vivo
Neohesperidin, administered at a dose of 50 mg/kg, significantly reduces the occurrence of HCl/ethanol-induced gastric lesions by 55.0%. In studies involving pylorus-ligated rats, this compound notably decreases both the volume of gastric secretion and gastric acid output, while simultaneously increasing gastric pH[1]. Additionally, neohesperidin treatment markedly improves glucose metabolism and insulin sensitivity in diabetic mice, evidenced by substantial reductions in fasting glucose, serum glucose, glycosylated serum protein (GSP), serum triglycerides, total cholesterol, and leptin levels, alongside a decrease in the liver index. It also enhances oral glucose tolerance and reduces insulin resistance in these mice[3].
AliasNSC 31048, Hesperetin 7-O-neohesperidoside
Chemical Properties
Molecular Weight610.56
FormulaC28H34O15
Cas No.13241-33-3
SmilesO=C1C=2C(O[C@@H](C1)C3=CC(O)=C(OC)C=C3)=CC(O[C@H]4[C@H](O[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@@H](CO)O4)=CC2O
Relative Density.1.447 g/cm3. Temperature:20 °C.;1.447 g/cm3. Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (81.89 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6378 mL8.1892 mL16.3784 mL81.8920 mL
5 mM0.3276 mL1.6378 mL3.2757 mL16.3784 mL
10 mM0.1638 mL0.8189 mL1.6378 mL8.1892 mL
20 mM0.0819 mL0.4095 mL0.8189 mL4.0946 mL
50 mM0.0328 mL0.1638 mL0.3276 mL1.6378 mL

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