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ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actinidiae (Psa). ROS inducer 1 induces ROS production in Xanthomonas cells and can be used to study bacterial infections in crops.

ROS kinases-IN-2 is a potent ROS kinase inhibitor with an inhibition rate of 21.53% measured at 10 μM.ROS kinases-IN-2 has potential anticancer activity and can be used to study abnormal cell growth.

Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.

ROS kinases-IN-1 is a ROS tyrosine kinase inhibitor with IC50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity.

ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage by curtailing the generation of oxidative stressors. It has applications in myocardial ischemia/reperfusion (MI/R) injury research [1].

Compound I16 (ROS inducer 2) is a potent inducer of Reactive Oxygen Species (ROS) with an effective concentration (EC 50) of 3.43 μg/mL demonstrated in vitro. It exhibits exceptional bioactivity in vivo against Xanthomonas axonopodis pv. citri and has potential as a bactericidal agent for investigating intractable plant bacterial diseases [1].

ROS 234 is a highly effective H3 antagonist, demonstrating a strong binding affinity (pK B) of 9.46 for the Guinea-pig ileum H3 receptor and a pKi of 8.90 for the Rat cerebral cortex H3 receptor. Additionally, it exhibits an ex vivo ED50 of 19.12 mg/kg (ip) in the Rat cerebral cortex. It should be noted that ROS 234 demonstrates limited central access, as reported in [1] and [2].

Compound I6 (ROS inducer 3) is a potent ROS inducer with robust in vitro bioactivity, demonstrated by an EC50 of 2.86 μg/mL. It exhibits significant protective activity against Pseudomonas syringae pv. actinidiae, and as a bactericidal agent, shows promise for research into challenging plant bacterial diseases [1].

ROS-ERS inducer 1, a type II immunogenic cell death (ICD) inducer, is a Pt(II)-N-heterocyclic carbene (Pt(II)-NHC) complex derived from 4,5-diarylimidazole. It induces endoplasmic reticulum stress (ERS) along with reactive oxygen species (ROS) generation, leading to the release of damage-associated molecular patterns (DAMPs) in HCC cells, showcasing significantly higher anticancer activities than Cisplatin [1].

ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor)

ROS tracer precursor, the synthesis precursor for [18F]ROStrace, serves in the production of ROStrace. This compound is instrumental in disease diagnosis.

ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities.

ROS1-IN-1 (Compound 31) is a highly effective and specific inhibitor of the ROS1 kinase, displaying a remarkable inhibitory concentration (IC 50) of 0.097 μM [1].

Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis. Ferrostatin-1 potently inhibits Erastin-induced ferroptosis in HT-1080 cells with an EC50 of 60 nM. Ferrostatin-1 also exhibits antioxidant and antifungal activities.

Syrosingopine has selective depleting effect on brain amines is potentiated by combined treatment with disulfiram or fusaric acid, a dopamine beta-hydroxylase inhibitor.

Uprosertib (GSK2141795) (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.

Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).

Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO.

Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.

Pterostilbene is extracted from Pterocarpus indicus.

1. Sweroside possesses strong hepatoprotective effect. 2. Sweroside is a promising osteoporosis therapeutic natural product, has anti-osteoporotic effect on the human MG-63 cells and rat osteoblasts.

Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid) is a microbially associated metabolite. Desaminotyrosine protects from influenza through augmentation of type I interferon signaling.

Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.

Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.

Androsterone, a metabolic product of testosterone, can activate Farnesoid X Receptor (FXR).

Tyrosine kinase-IN-7 is a potent inhibitor of the tyrosine kinase EGFR, inhibiting EGFR(WT) and EGFR(T790M) and showing anti-cancer and anti-tumor activity in a variety of cancer cell lines. Tyrosine kinase-IN-7 has potential anti-inflammatory and antiviral activities.

3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the p38MAPK , and PI3K/Akt/mTOR/p70S6K pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].

Sucrose octaacetate is an acetylated derivative of sucrose. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, and other toxic products as a deterr

Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-α and IL-6, the m

N-Nitroso-N-methylurea is a nitrosourea compound with alkylating, carcinogenic and mutagenic properties. It targets a variety of animal organs, causes various cancers and degenerative diseases, and can be used in diazomethane synthesis.

N-Acetyl-L-tyrosine (Ac-Tyr-OH) is a side chain reaction of tyrosine. It converts to tyrosine and then can be used in neurotransmitter treatment as a precursor of cathecholamine.

1. Paederoside is a potent deterrent against the beetle was isolated from the aphid . 2. Paederoside displays high anti-tumor promoting activity against the Epstein-Barr virus activation.

Spirostan-3-ol (Sarsaponin) is a stereoisomer of Sarsasapogenin (S142505), a steroid glycoside isolated from plant materials. A saponin with with potential anti-tumor activity via apoptosis.

Erythrosin B (Iodeosin) , a tetraiodofluorescein, is used as a red coloring in some foods (cherries, fish), as a stain of some cell types, and as a disclosure of DENTAL PLAQUE. Its molecular structure is similar to THYROXINE.

Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol) is a natural product with anticancer and hemolytic properties [1].

Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.

Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) is a novel 5 alpha-reductase inhibitor.The antiprostatic effect of Isomer-Turosteride in adult rats is associated with the inhibition of the conversion of T to DHT.Isomer-Turosteride induces a decrease in prostate DHT independent of a secondary increase in T. Isomer-Turosteride has anticancer activity and inhibits the growth of tumor cells. Turosteride has anticancer activity and inhibits the growth of tumor cells. Translated with www.DeepL.com/Translator (free version)

Tyrosyltyrosine acetate is a peptide.

Syringopicroside (2-(4-hydroxyphenyl)ethyl (1S,4aS,7R)-7-methyl-6-oxo-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carboxylate) is a natural drug with antibacterial activity from Syringa oblata Lindl (S. oblata).

Linaroside exhibited 30% inhibition for antimycobacterial activity against Mycobacterium tuberculosis, strain H(37)Rv at 6.25 microg mL(-1) concentration.

Rosthornin A is a kind of natural product derived from the herbs of Rabdosia rosthornii.

Tyroserleutide (YSL), isolated from the degradation products of porcine spleen, is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo.Tyroserleutide inhibits the growth and metastasis of human hepatocellular carcinoma (HCC)

Anhydrosimvastatin (Dehydro simvastatin) is an impurity of Simvastatin. Simvastatin is an HMG-CoA reductase inhibitor.

N-Noratherosperminine hydrochloride is alkaloid hydrochloride. Noratherosperminine has been extracted from Cryptocarya nigra.

9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells.

5-MethoxyPinocembroside is a flavonoid isolated from leaves of Moringa oleifera.

N′-(2-Chloroethyl)-N-(4-methylcyclohexyl)-N-nitrosourea has antitumor activity and is used in the treatment of Lewis lung and colon tumors.

4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone is a microbial metabolism of yangonin, a major styryl lactone from Piper methysticum.

Enterostatin, human, mouse, rat acetate is a pentapeptide mainly formed in the intestine by the cleavage of secreted pancreatic procolipase.

Limocitrin 3-O-sophoroside is a compound that can be used in biological research.