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Roslin 2 bromide
🥰Excellent
Catalog No. T24730Cas No. 29574-21-8
Alias Roslin-2, Roslin2, Benzylhexamethylenetetramine bromide
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5, exhibiting anticancer effects.
Roslin 2 bromide
🥰Excellent
Purity: 97.07%
Catalog No. T24730Alias Roslin-2, Roslin2, Benzylhexamethylenetetramine bromideCas No. 29574-21-8
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5, exhibiting anticancer effects.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $44 | In Stock | |
| 5 mg | $98 | In Stock | |
| 10 mg | $148 | In Stock | |
| 25 mg | $252 | In Stock | |
| 50 mg | $375 | In Stock | |
| 100 mg | $552 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $108 | In Stock |
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Purity:97.07%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5, exhibiting anticancer effects. |
| In vitro | Roslin 2 bromide reduces cancer cell viability and clonogenicity in a p53-dependent manner[1]. |
| In vivo | Roslin 2 bromide (60 mg/kg; i.p) significantly decreased tumor growth, disrupts the complex of FAK and p53, and up-regulated p21 in HCT116 p53+/+ but not in HCT116 p53-/- xenografts[1]. |
| Alias | Roslin-2, Roslin2, Benzylhexamethylenetetramine bromide |
| Molecular Weight | 311.22 |
| Formula | C13H19BrN4 |
| Cas No. | 29574-21-8 |
| Smiles | [Br-].C(c1ccccc1)[N+]12CN3CN(CN(C3)C1)C2 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (144.59 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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