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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $97 | In Stock | |
5 mg | $197 | In Stock | |
10 mg | $282 | In Stock | |
25 mg | $497 | In Stock | |
50 mg | $723 | In Stock | |
100 mg | $987 | In Stock | |
500 mg | $1,980 | In Stock | |
1 mL x 10 mM (in DMSO) | $198 | In Stock |
Description | Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5. Roslin 2 bromide exhibits anticancer effects. |
In vitro | Roslin 2 bromide decreases cancer cell viability and clonogenicity in a p53-dependent manner[1]. |
In vivo | Roslin 2 bromide (60 mg/kg; i.p) significantly decreased tumor growth, disrupts the complex of FAK and p53, and up-regulated p21 in HCT116 p53+/+ but not in HCT116 p53-/- xenografts[1]. |
Alias | Roslin-2, Benzylhexamethylenetetramine bromide, Roslin2 |
Molecular Weight | 311.22 |
Formula | C13H19BrN4 |
Cas No. | 29574-21-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (144.59 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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