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DPBQ
Catalog No. T11092Cas No. 7029-89-2
Alias ZINC1620467, 2,3-Diphenylbenzo[g]quinoxaline-5,10-dione
DPBQ (ZINC1620467) is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA.
DPBQ
Catalog No. T11092Alias ZINC1620467, 2,3-Diphenylbenzo[g]quinoxaline-5,10-dioneCas No. 7029-89-2
DPBQ (ZINC1620467) is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $107 | In Stock | |
| 2 mg | $161 | In Stock | |
| 5 mg | $273 | In Stock | |
| 10 mg | $394 | In Stock | |
| 25 mg | $592 | In Stock | |
| 50 mg | $816 | In Stock | |
| 100 mg | $1,090 | In Stock | |
| 500 mg | Inquiry | In Stock |
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Purity:98.73%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | DPBQ (ZINC1620467) is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA. |
| In vitro | DPBQ induces apoptosis and death and selectively affects 4N cells.DPBQ can specifically induce the expression and phosphorylation of p53.Deletion of TP53 can restore the proliferation of tetraploid cells in the presence of DPBQ. |
| Alias | ZINC1620467, 2,3-Diphenylbenzo[g]quinoxaline-5,10-dione |
| Molecular Weight | 362.38 |
| Formula | C24H14N2O2 |
| Cas No. | 7029-89-2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
| Solubility Information | DMSO: 2.5 mg/mL (6.9 mM), Sonication and heating to 80℃ are recommended. | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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