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TargetMol | Compound Library

Membrane Protein-targeted Compound Library

Catalog No. L1520

Membrane proteins are a class of proteins widely found in biological cell membranes, playing essential roles in the structure and function of cells. Based on their location and function, membrane proteins can be classified into three main categories: peripheral membrane proteins, integral membrane proteins, and lipid-anchored proteins. Membrane proteins encompass a variety of functional proteins, including glycoproteins, carrier proteins, and enzymes. They are often linked to carbohydrate molecules, which can transmit signals into the cell by undergoing structural changes, participating in signal transduction processes. Membrane proteins perform a range of critical functions, including substance transport, signal transduction, cell recognition, and energy conversion. In drug development, membrane proteins, especially G protein-coupled receptors (GPCRs), ion channels, and transporters, are of particular interest. Many diseases are related to the malfunction of specific membrane proteins. Therefore, drugs designed to target these proteins can regulate their activity, aiming to treat diseases. TargetMol has collected 6422 compounds that target membrane proteins, which can be used for membrane protein-related scientific research and drug screening, suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1520

Membrane Protein-targeted Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 6422 small molecules targeting various membrane proteins.
  • Structurally diverse, highly effective, and cell-permeable.
  • Detailed compound information with structure, target, activity, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are in stock and continuously updated.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

5-HT Receptor
Apoptosis
AChR
Autophagy
Adrenergic Receptor
Dopamine Receptor
Calcium Channel
Potassium Channel
EGFR
Histamine Receptor
Sodium Channel
GABA Receptor
Endogenous Metabolite
VEGFR
GluR
Histone Methyltransferase
TRP/TRPV Channel
GPR
Cholinesterase (ChE)
JAK
p38 MAPK
Antibacterial
Prostaglandin Receptor
Src
Adenosine Receptor
Opioid Receptor
PKC
FLT
Estrogen Receptor/ERR
PDGFR
iGluR
Caspase
RAAS
NF-κB
GSK-3
MMP
FGFR
NO Synthase
Raf
CDK
c-Kit
c-Met/HGFR
TLR
ATPase
Parasite
Cannabinoid Receptor
Bcr-Abl
HSP
TGF-beta/Smad
TNF
ALK
COX
Estrogen/progestogen Receptor
PKA
Aurora Kinase
Kras
Wnt/beta-catenin
NMDAR
BTK
Ras
HER
P-gp
ERK
CCR
Akt
Tyrosine Kinases
ROCK
Cytochromes P450
Antibiotic
CXCR
Neurokinin receptor
HIV Protease
Serotonin Transporter
Casein Kinase
Integrin
IGF-1R
P2X Receptor
S1P Receptor
Reactive Oxygen Species
Hedgehog/Smoothened
c-RET
FAK
LPL Receptor
IL Receptor
Norepinephrine
Trk receptor
TAM Receptor
STAT
Sigma receptor
Glucagon Receptor
Proton pump
PDE
Chloride channel
Neuropeptide Y Receptor
PPAR
transporter
Influenza Virus
c-Fms
Syk
Antifungal
CFTR
Cysteine Protease
Endothelin Receptor
Protease-activated Receptor
PI3K
SARS-CoV
cholecystokinin
cAMP
Ferroptosis
Antioxidant
P2Y Receptor
DYRK
JNK
Leukotriene Receptor
Drug Metabolite
SGLT
Melanocortin Receptor
NOS
Vasopressin Receptor
DNA/RNA Synthesis
LPA Receptor
Bradykinin Receptor
OX Receptor
Interleukin
AMPK
Mitophagy
GNRH Receptor
Guanylate cyclase
Bcl-2 Family
MRP
Epigenetic Reader Domain
MEK
GTPase
Virus Protease
Rho
ROS
mTOR
S6 Kinase
ROS Kinase
PARP
Lipoxygenase
CaMK
MAPK
Ephrin Receptor
Beta Amyloid
GHSR
HCV Protease
ABC Transporter
Phospholipase
Tyrosinase
Neurotensin Receptor
CSF-1R
Smo
HSV
Somatostatin
HDAC
CaSR
GPCR19
Serine/threonin kinase
Topoisomerase
Monoamine Transporter
Discoidin Domain Receptor (DDR)
Arrestin
MAO
PAFR
GRK
Antiviral
Monocarboxylate transporter
Melatonin Receptor
Glucocorticoid Receptor
Antifection
Bombesin Receptor
BCRP
Adenylyl Cyclase
Carbonic Anhydrase
Phosphatase
Serine Protease
Immunology/Inflammation related
Mitochondrial Metabolism
OAT
CRFR
IκB/IKK
CGRP Receptor
Anti-infection
Microtubule Associated
Melanin-concentrating Hormone Receptor (MCHR)
Apelin receptor
Dehydrogenase
Na+/Ca2+ Exchanger
Tie-2
PYK2
Annexin A
LTR
OCT
HBV
Pim
MT Receptor
Chk
Nrf2
TSH Receptor
Oxytocin Receptor
p53
CRM1
BACE
FXR
HIF
NOD
HIF/HIF Prolyl-Hydroxylase
MLK
Proteasome
Transferase
NPC1L1
Progesterone Receptor
Myosin
RIP kinase
LDL
HCN Channel
FAAH
ACK1
Androgen Receptor
Beta-Secretase
Acyltransferase
PLK
DNA Methyltransferase
AhR
Monoamine Oxidase
Reductase
Histone Demethylase
NADPH
Kisspeptin
VDAC
IAP
Adiponectin Receptor
Glucosidase
Fatty Acid Synthase
DNA
PGE Synthase
Free radical scavengers
Sirtuin
RSV
GST
Aquaporin
SGK
Platelet aggregation
IRAK
Thrombin
NOD-like Receptor (NLR)
Imidazoline Receptor
Transaminase
ROR
MyD88
Glutathione Peroxidase
Hck
Nucleoside Antimetabolite/Analog
E1/E2/E3 Enzyme
Na-K-Cl cotransporter
Histone Acetyltransferase
Reverse Transcriptase
ribosome
CRISPR/Cas9
PDK
Hydroxylase
HMG-CoA Reductase
DHFR
Piezo Channel
DNA-PK
EBI2/GPR183
Amino Acids and Derivatives
YAP
Arginase
Sodium-dependent phosphate transporter
IFNAR
PERK
gp120/CD4
c-Myc
AAK1
Antifolate
Cell Cycle Arrest
LIM Kinase
Glucokinase
Glutaminase
Aryl Hydrocarbon Receptor
IRE1
UGT
Gamma-secretase
DNA gyrase
PAK
Stearoyl-CoA Desaturase (SCD)
PTEN
DUB
Indoleamine 2,3-Dioxygenase (IDO)
MNK
Porcupine
LRRK2
GluCls
PAI-1
Pyroptosis
MELK
Retinoid Receptor
Aromatase
IGF-2R
NADPH-oxidase
Amylin Receptor
Thyroid hormone receptor(THR)
Mdm2
GSNOR
Dynamin
Glutaminyl Cyclase
Neuropeptide W
RAR/RXR 
TOPK
N-Acetylglucosaminyltransferase
Liver X Receptor
NAMPT
Amylase
FLAP
Motilin Receptor
Haspin Kinase
Phosphorylase
GlyT
Anion Exchanger
DNA Alkylation
Angiotensin-converting Enzyme (ACE)
PAD
Thrombopoietin Receptor
ATP Citrate Lyase
Lipid
Wee1
Huntingtin
Survivin
MRGPR
Aminopeptidase
AIM2
Neprilysin
Hippo pathway
ATM/ATR
GPX
Protease
RXFP receptor
Adenosine Deaminase
Complement System
Gap Junction Protein
DAPK
Lysosomal Autophagy
p97
PD-1/PD-L1
Kinesin
PKM

Keywords