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ent-8-iso-15(S)-Prostaglandin F2α

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Catalog No. T35990Cas No. 214748-66-0
Alias ent-8-iso-15(S)-Prostaglandin F2α

Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.

ent-8-iso-15(S)-Prostaglandin F2α
Other Forms of ent-8-iso-15(S)-Prostaglandin F2α:
ent-Prostaglandin F2αT3599254483-31-7
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ent-8-iso-15(S)-Prostaglandin F2α

😃Good
Catalog No. T35990Alias ent-8-iso-15(S)-Prostaglandin F2αCas No. 214748-66-0
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.
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25 μg$29435 days
50 μg$57035 days
100 μg$1,07035 days
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Product Introduction

Bioactivity
Description
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.
Aliasent-8-iso-15(S)-Prostaglandin F2α
Chemical Properties
Molecular Weight354.48
FormulaC20H34O5
Cas No.214748-66-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
PBS (pH 7.2): >10 mg/mL
DMF: >100 mg/mL
DMSO: >100 mg/mL
10 mM Na2CO3: >6.5 mg/mL
Ethanol: >100 mg/mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

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