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α-Thujone

Catalog No. T8193Cas No. 546-80-5
Alias Thujone, ALPHA-(-)-THUJONE

α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.

α-Thujone

α-Thujone

Purity: 98.41%
Catalog No. T8193Alias Thujone, ALPHA-(-)-THUJONECas No. 546-80-5
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
Pack SizePriceAvailabilityQuantity
10 mg$31In Stock
25 mg$48In Stock
50 mg$72In Stock
100 mg$122In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:98.41%
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Product Introduction

Bioactivity
Description
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
Targets&IC50
α7 nACh:24.7μM
In vitro
In in-vivo one-trial passive avoidance paradigm show that thujone (1.25mg/kg, i.p.) significantly impaired nicotine-induced enhancement of learning and memory in Wistar rats[1].
AliasThujone, ALPHA-(-)-THUJONE
Chemical Properties
Molecular Weight152.23
FormulaC10H16O
Cas No.546-80-5
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 4.4 mg/mL (28.9 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.5690 mL32.8450 mL65.6901 mL328.4504 mL
5 mM1.3138 mL6.5690 mL13.1380 mL65.6901 mL
10 mM0.6569 mL3.2845 mL6.5690 mL32.8450 mL
20 mM0.3285 mL1.6423 mL3.2845 mL16.4225 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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