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Tributyrin

🥰Excellent
Catalog No. T19676Cas No. 60-01-5
Alias NSC-661583, NSC661583, NSC 661583

Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.

Tributyrin

Tributyrin

🥰Excellent
Purity: 97.79%
Catalog No. T19676Alias NSC-661583, NSC661583, NSC 661583Cas No. 60-01-5
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.
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5 mL$50In Stock
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Purity:97.79%
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Product Introduction

Bioactivity
Description
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. It diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into cells in vivo, exhibiting potent proapoptotic, antiproliferative, and differentiation-inducing effects.
AliasNSC-661583, NSC661583, NSC 661583
Chemical Properties
Molecular Weight302.36
FormulaC15H26O6
Cas No.60-01-5
SmilesCCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC
Relative Density.1.032g/mLat 20°C(lit.)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (330.73 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3073 mL16.5366 mL33.0732 mL165.3658 mL
5 mM0.6615 mL3.3073 mL6.6146 mL33.0732 mL
10 mM0.3307 mL1.6537 mL3.3073 mL16.5366 mL
20 mM0.1654 mL0.8268 mL1.6537 mL8.2683 mL
50 mM0.0661 mL0.3307 mL0.6615 mL3.3073 mL
100 mM0.0331 mL0.1654 mL0.3307 mL1.6537 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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