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TargetMol | Compound Library

RO5 Drug-like Natural Product Library

Catalog No. L6160

Natural products are important sources of lead compounds and drug candidates. They have complex scaffold structures and rich functional groups. Their structures are unique, and most of them are chiral. These naturally occurring advantages provide more diverse options for the transformation of natural products into drugs, and are also the reasons why natural products play an important role in drug development and research. Based on the structural diversity and novelty of natural products, TargetMol used the druglikeness prediction index "Lipinski's Rule of Five" to select 2703 natural product monomers with good druggabilities, covering diverse structures from vast sources such as terpenes and alkaloids. The library is consisted of monomers with both biological activity and drug-like properties. It is a powerful tool for subsequent structure-effect optimization and innovative drug research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L6160

RO5 Drug-like Natural Product Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • 2703 is a collection of natural products that meet the "Lipinski's Rule of Five" and have high potential for drug discovery.
  • Most of the NPs have clear biological activities, with various functions including anti-tumor, anti-inflammatory, antioxidant, neuroprotection and more.
  • Structural diversity, containing flavonoids, saponins, terpenoids, alkaloids and other categories.
  • Various detection techniques such as NMR, HPLC/LCMS to ensure accurate structure and high purity of the products and reduce false positives.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Endogenous Metabolite
Apoptosis
Antibacterial
Autophagy
NF-κB
Antifungal
Antibiotic
Reactive Oxygen Species
Parasite
Antioxidant
COX
P450
AChR
Influenza Virus
Anti-infection
DNA/RNA Synthesis
AChE
TNF
p38 MAPK
GABA Receptor
IL Receptor
Caspase
ERK
Tyrosinase
Calcium Channel
HIV Protease
Akt
5-HT Receptor
Ferroptosis
STAT
NO Synthase
Estrogen/progestogen Receptor
Adrenergic Receptor
Topoisomerase
Virus Protease
AMPK
TRP/TRPV Channel
Nrf2
PI3K
PPAR
MMP
Estrogen Receptor/ERR
ROS
Lipoxygenase
NOS
Dopamine Receptor
BCL
PDE
Antifection
PKC
Potassium Channel
Dehydrogenase
JNK
PARP
Microtubule Associated
Nucleoside Antimetabolite/Analog
HSV
EGFR
Mitophagy
Adenosine Receptor
Histamine Receptor
iGluR
Drug Metabolite
Prostaglandin Receptor
HDAC
Amino Acids and Derivatives
Glucosidase
Mitochondrial Metabolism
Antiviral
Sodium Channel
Wnt/beta-catenin
VEGFR
MAO
GluR
Androgen Receptor
P-gp
HIF/HIF Prolyl-Hydroxylase
ATPase
Immunology/Inflammation related
Glucocorticoid Receptor
NMDAR
JAK
HBV
CDK
SARS-CoV
Monoamine Oxidase
Opioid Receptor
Sirtuin
HCV Protease
Progesterone Receptor
TGF-beta/Smad
TLR
Phospholipase
NOD
Chloride channel
PKA
Fatty Acid Synthase
mTOR
Indoleamine 2,3-Dioxygenase (IDO)
Interleukin
MAPK
IκB/IKK
Beta Amyloid
GPR
HIF
HMG-CoA Reductase
Carbonic Anhydrase
Transferase
Src
Reductase
BACE
NADPH
Phosphatase
FXR
Aryl Hydrocarbon Receptor
PAFR
Gamma-secretase
Xanthine Oxidase
transporter
Reverse Transcriptase
Cannabinoid Receptor
Platelet aggregation
AhR
HER
Arginase
c-Met/HGFR
Serine/threonin kinase
UGT
LDL
cAMP
ATP Citrate Lyase
PGE Synthase
HSP
MEK
FGFR
Syk
DNA Methyltransferase
p53
Thyroid hormone receptor(THR)
Proton pump
DHFR
ROR
Integrin
Glutathione Peroxidase
GSK-3
MRP
Tyrosine Kinases
Serotonin Transporter
IAP
Hedgehog/Smoothened
CCR
Epigenetic Reader Domain
CaMK
Telomerase
Lipid
Beta-Secretase
Trk receptor
Free radical scavengers
GPCR19
GST
ribosome
Aromatase
FAK
Imidazoline Receptor
Proteasome
LTR
DYRK
RAAS
gp120/CD4
c-Myc
Serine Protease
Cysteine Protease
RANKL/RANK
Amylase
E1/E2/E3 Enzyme
Phosphorylase
DNA gyrase
Smo
DPP-4
PDGFR
PAK
FAAH
CXCR
Aurora Kinase
IGF-1R
DNA
OAT
Aminopeptidase
Decarboxylase
PAI-1
Casein Kinase
ATM/ATR
PDK
Ras
Thrombin
NOD-like Receptor (NLR)
PKM
advanced glycation end products
Mdm2
Adenylyl cyclase
CAT
Transaminase
Monocarboxylate transporter
Hydrogenase
CD38
CYP19A1
LPL Receptor
DNA Alkylator/Crosslinker
P2Y Receptor
aconitase
RAR/RXR 
Factor Xa
Melatonin Receptor
OCT
ABC
Pim
Antifolate
Liver X Receptor
Leukotriene Receptor
IDO
Prolyl Endopeptidase (PREP)
IRE1
Adiponectin receptor
Raf
MT Receptor
P2X Receptor
GlyT
Hexokinase
Monoamine Transporter
Stearoyl-CoA Desaturase (SCD)
Somatostatin
PAD
Norepinephrine
SGLT
BCRP
Acyltransferase
Histone Acetyltransferase
hCE
Pyroptosis
ALK
Carboxypeptidase
Retinoid Receptor
CRISPR/Cas9
Hydroxylase
PLK
ATTECs
Neurokinin receptor
NMU2R
FLT
NADPH-oxidase
IRAK
S6 Kinase
ROS Kinase
CFTR
PD-1/PD-L1
S1P Receptor

Keywords