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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
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TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

FDA-Approved Drug Library

Catalog No. L4200
  Library Compound List   Excel SDF

All compounds in FDA approved drug library have well-characterized biological activity, clear targets, safety, and bioavailability – properties which could dramatically accelerate drug development and optimization. It is an effective and ideal tool for drug repurposing and cell differentiation induction. Detailed information on each compound in this library can help scientists quickly finish drug screening or make quick judgement on cell differentiation mechanism, and create conditions for further investigation on the mechanism of action.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 1729 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research evidence and clinical trials;
  • An effective tool for discovering new with old drugs and new drug target identification;
  • Covers various research areas: oncology, cardiology, anti-inflammatory, immunology, neuropsychiatry, analgesia etc
  • Structurally diverse, medicinally active, and cell permeable;
  • Rich documentation with structure, target, IC50 value and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L4200)

Publications Cited TargetMol Libraries

1. Nature Biotechnology. 2021, 39(11): 1444-1452. 2. ACS Central Science. 2023. 3. Nature Communications. 2023, 14(1): 2756.. 4. Nature Communications. 2023, 14(1): 1020.. 5. Blood. 2021, 137(11): 1478-1490. 6. Advanced Science. 2021: 2101957. 7. Protein & Cell. 2021: 1-19.. 8. Bone Research. 2023, 11(1): 54. 9. Journal of Experimental & Clinical Cancer Research. 2023, 42(1): 1-27..
10. Pharmacology & Therapeutics. (2021): 107930. 11. Microbial Biotechnology. 2022, 15(2): 482-498. 12. Journal of Translational Medicine. 2022, 20(1): 1-11.. 13. Cancer Research. 2020. 14. Neuropsychopharmacology. 2022: 1-9. 15. Theranostics. 2020, 10(13): 5749-5762. 16. PLoS Biology. 2021, 19(10): e3001425. 17. Journal of Medicinal Chemistry. 2023. 18. Immunology. 2023;1–10.. 19. Microbiology Spectrum. 2022: e00884-22. 20. Elife. 2021, 10: e65962. 21. Translational Research. 2022. 22. European Journal of Medicinal Chemistry. 2023: 116018.. 23. International Journal of Molecular Sciences. 2022, 23(19): 11250. 24. Fundamental Research. 2023. 25. Cell Death & Disease. 2020, 11(3): 1-12. 26. International Journal of Molecular Sciences. 2022, 23(7): 4050. 27. International Journal of Molecular Sciences. 2020. 28. Viruses. 2021 Jun 3;13(6):1061. 29. International Journal of Oncology. 2022, 60(6): 1-13. 30. Journal of Molecular Cell Biology. 2023: mjad056. 31. Journal of Virus Eradication. 2023: 100327.. 32. Frontiers in Immunology. 2020, 11. 33. Scientific Reports. 2022 Nov 2;12(1):18506. 34. Molecules. 2022, 27(15): 5000.. 35. Antimicrobial agents and chemotherapy. 2021, 65(4): e02577-20. 36. Antimicrobial Agents and Chemotherapy. 2020, 64(9). 37. CNS Oncology. 2020. 38. Viruses. 2023, 15(8): 1666.. 39. ACS Infectious Diseases. 2021 Aug 13;7(8):2337-2351. 40. Journal of virology. 2018, 92(20): e01018-18.. 41. Virologica Sinica. 2022. 42. Journal of Proteome Research. 2020. 43. Journal of Biological Chemistry. 2016 Apr;291(17): 9218-9232.. 44. Acta Pharmacologica Sinica, 2019, 40(12): 1568-1577. 45. Neoplasia. 2020, 22(4): 179-191. 46. Virology. 2022. 47. Molecular Informatics. 2022. 48. Journal of Biomolecular Structure and Dynamics. 2020: 1-16. 49. Journal of Clinical Medicine. 2020, 9(5): 1473. 50. RSC Advances. 2021, 11(4): 2158-2166. 51. Orthopaedic Surgery. 2023. 52. Interdisciplinary Sciences: Computational Life Sciences, 2020, 12: 368-376. 53. Hollis R L, Elliott R, Dawson J C, et al.High throughput screening identifies dasatinib as synergistic with trametinib in low grade serous ovarian carcinoma.Gynecologic Oncology.2024, 186: 42-52. 54. Dou X, Huo T, Liu Y, et al.Discovery of novel and selective farnesoid X receptor antagonists through structure-based virtual screening, preliminary structure-activity relationship study, and biological evaluation.European Journal of Medicinal Chemistry.2024: 116323. 55. bioRxiv. 2023: 2023.05. 24.542186.. 56. SSRN. 2023. 57. bioRxiv. 2021. 58. AIP Publishing LLC. 2021, 2370(1): 070005. 59. researchsquare. 2022. 60. Chemrxiv. 2020. 61. Cell Stem Cell. 2022 Apr 29(4) 545–558. 62. Science Bulletin. 2022. 63. Science Translational Medicine. 2022, 14(656): eabn3231. 64. Science Advances. 2023, 9(9): eade3760. 65. Nature. 2020, 582: 289-293. 66. Nature Communications. 2022, 13(1): 1-15.. 67. Nucleic Acids Research. 2021. 68. Nature Communications. 2023, 14(1): 7574. 69. Advanced Science. 2020, 7(16): 2000925. 70. Angewandte Chemie. 2021. 71. Acta Pharmaceutica Sinica B. 2022. 72. Protein & Cell. 2021, 12(11): 877-888. 73. Nature Communications. 2021, 12(1): 1-12. 74. Journal of Cell Biology. 2022, 221(5): e202112024. 75. Liu T, Yue X, Chen X, et al.Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma.Cellular Oncology.2024: 1-18. 76. Fang Z Y, Zhang Z Y, Zheng Y D, et al.Repurposing cinacalcet suppresses multidrug-resistant Staphylococcus aureus by disruption of cell membrane and inhibits biofilm by targeting IcaR.Journal of Antimicrobial Chemotherapy.2024: dkae051.
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Library Composition

Antibacterial (256)
Autophagy (248)
Antibiotic (248)
Apoptosis (166)
Endogenous Metabolite (129)
Adrenergic Receptor (115)
5-HT Receptor (111)
AChR (82)
Histamine Receptor (75)
Dopamine Receptor (70)
HIV Protease (70)
COX (59)
Parasite (57)
Sodium Channel (57)
DNA/RNA Synthesis (54)
Antifungal (53)
Potassium Channel (48)
Glucocorticoid Receptor (43)
Calcium Channel (38)
Estrogen/progestogen Receptor (38)
P450 (34)
Topoisomerase (34)
Ferroptosis (30)
SARS-CoV (30)
RAAS (27)
Serotonin Transporter (27)
ribosome (26)
c-Kit (25)
VEGFR (25)
Dehydrogenase (24)
Mitophagy (24)
PDE (24)
GABA Receptor (23)
Microtubule Associated (23)
Antifection (22)
Reverse Transcriptase (22)
Nucleoside Antimetabolite/Analog (22)
Norepinephrine (21)
HSV (21)
HCV Protease (21)
PDGFR (20)
Estrogen Receptor/ERR (20)
Progesterone Receptor (20)
EGFR (17)
Proton pump (17)
PPAR (17)
Reactive Oxygen Species (17)
Influenza Virus (16)
Androgen Receptor (16)
Prostaglandin Receptor (15)
HBV (15)
ATPase (15)
JAK (15)
FLT (15)
Carbonic Anhydrase (14)
DNA Alkylator/Crosslinker (14)
FGFR (13)
Thrombin (13)
MAO (13)
Proteasome (12)
Src (12)
AChE (12)
Adenosine Receptor (12)
NF-κB (12)
ROS (11)
Raf (11)
Bcr-Abl (11)
Virus Protease (11)
c-Met/HGFR (11)
Tyrosine Kinases (11)
Monoamine Oxidase (10)
DHFR (10)
Transferase (10)
ALK (10)
MRP (10)
SGLT (9)
iGluR (9)
Antifolate (9)
HMG-CoA Reductase (9)
HDAC (9)
NO Synthase (9)
PI3K (9)
Drug Metabolite (9)
c-RET (9)
CDK (8)
GluR (8)
Phospholipase (8)
Retinoid Receptor (8)
P-gp (8)
mTOR (8)
MMP (8)
Opioid Receptor (8)
Thyroid hormone receptor(THR) (8)
Phosphatase (8)
ABC (8)
PARP (8)
TRP/TRPV Channel (8)
DNA gyrase (7)
HIF/HIF Prolyl-Hydroxylase (7)
DNA Methyltransferase (7)
MEK (7)
P2Y Receptor (7)
Factor Xa (7)
CaMK (7)
PKC (7)
DPP-4 (7)
DNA Alkylation (6)
S1P Receptor (6)
NMDAR (6)
LPL Receptor (6)
STAT (6)
Trk receptor (6)
CAT (6)
Endothelin Receptor (6)
TAM Receptor (6)
Histone Methyltransferase (5)
Hedgehog/Smoothened (5)
IL Receptor (5)
TNF (5)
Neurokinin receptor (5)
Guanylate cyclase (5)
TLR (5)
Ras (5)
GPR (5)
ERK (5)
Nrf2 (5)
ROS Kinase (5)
CFTR (5)
Lipoxygenase (5)
Monoamine Transporter (5)
Glutathione Peroxidase (4)
NADPH (4)
Antiviral (4)
FXR (4)
AMPK (4)
Integrin (4)
HER (4)
AhR (4)
Annexin A (4)
BTK (4)
Amino Acids and Derivatives (4)
HIF (4)
Hydroxylase (3)
GNRH Receptor (3)
Reductase (3)
Interleukin (3)
Akt (3)
Gamma-secretase (3)
NOS (3)
MT Receptor (3)
GST (3)
GPCR19 (3)
Decarboxylase (3)
Ligand for E3 Ligase (3)
Histone Demethylase (3)
Neprilysin (3)
DNA (3)
ROCK (3)
BCL (3)
Aryl Hydrocarbon Receptor (3)
Isocitrate Dehydrogenase (IDH) (3)
Fatty Acid Synthase (3)
Smo (3)
Cysteine Protease (3)
IGF-1R (3)
Molecular Glues (3)
PAK (3)
LDL (3)
Mitochondrial Metabolism (3)
Arginase (2)
c-Fms (2)
Cell wall (2)
Rho (2)
Beta Amyloid (2)
CCR (2)
Antioxidant (2)
Leukotriene Receptor (2)
IRE1 (2)
Integrase (2)
Adenosine deaminase (2)
Ligands for Target Protein for PROTAC (2)
UGT (2)
CETP (2)
CGRP Receptor (2)
CRM1 (2)
Gap Junction Protein (2)
Caspase (2)
Syk (2)
Sigma receptor (2)
Protease-activated Receptor (2)
Na-K-Cl cotransporter (2)
P2X Receptor (2)
Chloride channel (2)
PKM (2)
RSV (2)
Melanocortin Receptor (2)
Beta-Secretase (2)
Melatonin Receptor (2)
GluCls (2)
Glutathione reductase (2)
Lipid (2)
GSK-3 (2)
Xanthine Oxidase (2)
Thrombopoietin Receptor (2)
PGE Synthase (2)
Ephrin Receptor (2)
Free radical scavengers (2)
CaSR (2)
NOD-like Receptor (NLR) (1)
ROR (1)
Glucagon Receptor (1)
Epigenetic Reader Domain (1)
ATP Citrate Lyase (1)
Phosphorylase (1)
Platelet aggregation (1)
DNA-PK (1)
VDA (1)
DUB (1)
Anti-infection (1)
Telomerase (1)
NADPH-oxidase (1)
Adiponectin receptor (1)
GRK (1)
Hydrogenase (1)
TGF-beta/Smad (1)
Wnt/beta-catenin (1)
NPC1L1 (1)
Tyrosinase (1)
Glucosidase (1)
MTH1 (1)
GlyT (1)
Hexokinase (1)
Pyroptosis (1)
IAP (1)
OX Receptor (1)
CXCR (1)
Vasopressin Receptor (1)
IκB/IKK (1)
Angiotensin-converting Enzyme (ACE) (1)
Chk (1)
FAAH (1)
RAR/RXR  (1)
Somatostatin (1)
Serine Protease (1)
STING (1)
IFNAR (1)
JNK (1)
CRISPR/Cas9 (1)
CSF-1R (1)
Complement System (1)
HSP (1)
Oxytocin Receptor (1)
ACK (1)
YAP (1)
Aquaporin (1)
gp120/CD4 (1)
TOPK (1)
PROTAC Linker (1)
OAT (1)
PLK (1)
Myosin (1)
MAPK (1)
p38 MAPK (1)
PKA (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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