Pain-Related Compound Library

Catalog No. L2690

Pain: An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Pain reflects one’s health state as well as respiration, pulse, blood pressure, and body temperature. Pain can be categorized based on duration (acute pain & chronic pain), cause (nociceptive pain & neuropathic pain), sensory system (superficial pain & deep pain), and origin (visceral pain & somatic pain). Pain generation is a complex process involving multiple aspects, including physiological, psychological, and neurobiological factors. 1. Activate nociceptors: nociceptors are specialized sensory nerve endings distributed in the skin, internal organs, skeletal muscles, and joints that detect harmful stimuli. 2. Release pain-inducing substances: when tissue damage occurs, various pain-inducing substances are released, such as histamine, bradykinin, serotonin, acetylcholine, and prostaglandins. These substances can activate nociceptors. Additionally, the mechanisms of pain also encompass neural signal transmission, central regulation, psychological factors, and more. TargetMol has collected 2780 pain-related compounds used for related research.

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