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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
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CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Inhibitor Library

Catalog No. L2000
  Library Compound List   Excel SDF

Cell signalingis part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development,tissue repair, andimmunity, as well as normal tissuehomeostasis. Errors in signaling interactions and cellularinformation processingare responsible for diseases such as cancer,auto-immunity, and diabetes.By understanding cell signaling, diseases may be treated more effectively.

Inhibitor library is a unique collection of 8418 compounds, each of which has clear inhibitory targets. It is an effective tool for research in cell signaling pathways and related diseases, and high throughput screening and high content screening for new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 8418 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Covers various major targets including MAPK, PI3K, JAK, HDAC, VEGFR, CDK, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L2000)

Publications Cited TargetMol Libraries

1. Communications Biology. 2022, 5(1): 1-13. 2. Cell Stem Cell. 2022 Apr 29(4) 545–558. 3. Science Bulletin. 2022. 4. Science Translational Medicine. 2022, 14(656): eabn3231. 5. Science Advances. 2023, 9(9): eade3760. 6. Nature. 2020, 582: 289-293. 7. Nature Biotechnology. 2021, 39(11): 1444-1452. 8. Nature Communications. 2022, 13(1): 1-15.. 9. Nature Communications. 2023, 14(1): 1020..
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Library Composition

Apoptosis (787)
Autophagy (560)
Antibacterial (329)
5-HT Receptor (225)
CDK (214)
COX (186)
Endogenous Metabolite (184)
PI3K (180)
Antibiotic (173)
EGFR (171)
HIV Protease (167)
DNA/RNA Synthesis (164)
AChR (157)
VEGFR (156)
NF-κB (152)
PDE (150)
Dopamine Receptor (145)
Epigenetic Reader Domain (142)
Dehydrogenase (135)
P450 (128)
Adrenergic Receptor (126)
HDAC (122)
Histone Methyltransferase (121)
Histamine Receptor (117)
Parasite (116)
Potassium Channel (112)
JAK (103)
Calcium Channel (103)
mTOR (100)
FLT (99)
Phosphatase (98)
Antifungal (98)
Src (94)
Sodium Channel (91)
PDGFR (91)
Microtubule Associated (87)
Topoisomerase (83)
TRP/TRPV Channel (80)
FGFR (80)
PARP (79)
Raf (78)
AChE (77)
Wnt/beta-catenin (77)
ERK (75)
c-Kit (75)
SARS-CoV (75)
PKC (75)
Influenza Virus (74)
Akt (73)
p38 MAPK (72)
GSK-3 (72)
STAT (71)
HCV Protease (70)
Ras (69)
c-Met/HGFR (65)
MAO (65)
Proteasome (64)
Bcr-Abl (63)
RAAS (63)
Prostaglandin Receptor (62)
TNF (60)
Ferroptosis (60)
Reactive Oxygen Species (58)
Lipoxygenase (58)
ALK (57)
Aurora Kinase (57)
MMP (55)
GABA Receptor (55)
BCL (55)
Phospholipase (55)
HSP (54)
BTK (53)
DUB (52)
TGF-beta/Smad (50)
Virus Protease (47)
MAPK (47)
Casein Kinase (46)
Tyrosinase (46)
ROCK (46)
Tyrosine Kinases (46)
Adenosine Receptor (46)
Transferase (46)
NMDAR (45)
E1/E2/E3 Enzyme (45)
ATPase (44)
MEK (44)
Monoamine Oxidase (43)
NO Synthase (42)
Caspase (42)
HER (42)
Serine/threonin kinase (41)
Beta Amyloid (41)
iGluR (41)
GluR (41)
Histone Demethylase (41)
IL Receptor (41)
CCR (39)
Mitophagy (39)
HSV (39)
PKA (38)
JNK (38)
Sirtuin (38)
DNA-PK (38)
Reverse Transcriptase (38)
c-RET (37)
PPAR (37)
Mitochondrial Metabolism (37)
Cysteine Protease (37)
GPR (37)
Carbonic Anhydrase (37)
AMPK (36)
Serotonin Transporter (36)
TAM Receptor (35)
Antioxidant (35)
IκB/IKK (35)
Integrin (34)
HBV (34)
HIF (33)
Nucleoside Antimetabolite/Analog (33)
IGF-1R (33)
P-gp (33)
NOS (32)
ROS (32)
Gamma-secretase (32)
RIP kinase (31)
Drug Metabolite (31)
Proton pump (30)
Serine Protease (30)
Norepinephrine (30)
CXCR (30)
Histone Acetyltransferase (30)
CaMK (29)
PLK (29)
c-Fms (29)
Androgen Receptor (29)
S6 Kinase (29)
Estrogen Receptor/ERR (29)
Glucosidase (29)
TLR (29)
Estrogen/progestogen Receptor (28)
HIF/HIF Prolyl-Hydroxylase (28)
Reductase (28)
Trk receptor (27)
Interleukin (27)
FAAH (26)
P2X Receptor (26)
Hedgehog/Smoothened (26)
Antiviral (25)
Pim (25)
Syk (25)
DPP-4 (24)
Glucocorticoid Receptor (24)
Acyltransferase (24)
p53 (24)
FAK (24)
ATM/ATR (24)
Chk (23)
Kinesin (23)
Fatty Acid Synthase (22)
Indoleamine 2,3-Dioxygenase (IDO) (22)
NOD (21)
Cannabinoid Receptor (21)
SGLT (21)
Mdm2 (21)
DYRK (21)
Opioid Receptor (21)
HMG-CoA Reductase (21)
Anti-infection (20)
Thrombin (20)
S1P Receptor (20)
IRAK (20)
Neurokinin receptor (19)
Xanthine Oxidase (19)
LRRK2 (19)
transporter (19)
PDK (19)
LPL Receptor (19)
NADPH (19)
Chloride channel (19)
Antifection (18)
Rho (18)
Lipase (18)
DNA Methyltransferase (18)
Factor Xa (17)
PAK (17)
Endothelin Receptor (17)
Smo (17)
Nrf2 (17)
MRP (17)
Hydroxylase (16)
LTR (16)
Epoxide Hydrolase (16)
PD-1/PD-L1 (15)
PERK (15)
Aromatase (15)
Immunology/Inflammation related (15)
Glutathione Peroxidase (15)
P2Y Receptor (15)
IRE1 (15)
BACE (15)
PI4K (15)
YAP (14)
Retinoid Receptor (14)
OX Receptor (14)
Complement System (14)
Leukotriene Receptor (14)
DHFR (14)
ribosome (14)
Myosin (14)
CSF-1R (14)
Glucokinase (14)
Aryl Hydrocarbon Receptor (13)
Sigma receptor (13)
cAMP (13)
ROS Kinase (13)
c-Myc (13)
GTPase (13)
Ephrin Receptor (12)
LPA Receptor (12)
Neuropeptide Y Receptor (12)
AhR (12)
PGE Synthase (12)
Protease-activated Receptor (12)
Aminopeptidase (12)
DNA gyrase (11)
Stearoyl-CoA Desaturase (SCD) (11)
Lipid (11)
Monoamine Transporter (11)
Isocitrate Dehydrogenase (IDH) (11)
NOD-like Receptor (NLR) (11)
Antifolate (11)
Discoidin Domain Receptor (DDR) (11)
Beta-Secretase (11)
CETP (10)
Monocarboxylate transporter (10)
cholecystokinin (10)
PAI-1 (10)
IDO (10)
Acetyl-CoA Carboxylase (10)
DNA (10)
Vasopressin Receptor (10)
ATP Citrate Lyase (9)
Platelet aggregation (9)
STING (9)
GRK (9)
SGK (9)
Glutaminase (9)
Telomerase (9)
MLK (9)
IAP (9)
RSV (8)
CFTR (8)
MNK (8)
NAMPT (8)
ASK (8)
Neprilysin (8)
NADPH-oxidase (8)
BCRP (8)
Porcupine (8)
Phosphorylase (8)
GPX (7)
p97 (7)
Carboxypeptidase (7)
MAGL (7)
ABC (7)
UGT (7)
Adenylyl cyclase (7)
Dynamin (7)
Wee1 (7)
DNA Alkylator/Crosslinker (7)
Na+/Ca2+ Exchanger (7)
PAD (7)
Tie-2 (7)
GlyT (7)
Angiotensin-converting Enzyme (ACE) (7)
SIK (7)
GST (6)
AAK1 (AP2 associated kinase 1) (6)
OAT (6)
LDL (6)
FLAP (6)
MELK (6)
Progesterone Receptor (6)
Guanylate cyclase (6)
Thyroid hormone receptor(THR) (6)
DNA Alkylation (6)
Bombesin Receptor (5)
Survivin (5)
CRISPR/Cas9 (5)
Aquaporin (5)
Melanocortin Receptor (5)
LIM Kinase (5)
Neurotensin Receptor (5)
Adenosine deaminase (5)
PAFR (5)
MTH1 (5)
PTEN (5)
TOPK (5)
BMI-1 (5)
ACK (5)
DprE1 (5)
PYK2 (5)
Decarboxylase (5)
cGAS (5)
CRFR (5)
NPC1L1 (5)
Methionine Adenosyltransferase (MAT) (5)
APC (5)
Hippo pathway (5)
CRM1 (5)
OXPHOS (4)
NEDD8 (4)
DAPK (4)
KSP (4)
ROR (4)
Amino Acids and Derivatives (4)
Galectin (4)
CGRP Receptor (4)
GNRH Receptor (4)
MALT (4)
Imidazoline Receptor (4)
PKM (4)
advanced glycation end products (4)
MyD88 (4)
VDAC (4)
CD73 (4)
Amylase (4)
Protease (4)
Glucagon Receptor (4)
Bradykinin Receptor (4)
MT Receptor (4)
Gap Junction Protein (3)
Arginase (3)
Ligand for E3 Ligase (3)
Hexokinase (3)
CaSR (3)
Necroptosis (3)
Liver X Receptor (3)
Hck (3)
HCN Channel (3)
Pyroptosis (3)
Transaminase (3)
Haspin Kinase (3)
CAT (3)
IFNAR (3)
Melatonin Receptor (3)
Arrestin (2)
AIM2 (2)
EBI2/GPR183 (2)
Na-K-Cl cotransporter (2)
NUDIX hydrolase (2)
Integrase (2)
CD38 (2)
Melanin-concentrating Hormone Receptor (MCHR) (2)
GSNOR (2)
hCE (2)
FOXO1 (2)
GHSR (2)
FXR (2)
KLF (2)
Oxytocin Receptor (2)
Prolyl Endopeptidase (PREP) (2)
gp120/CD4 (2)
Cell wall (1)
PGC-1α (1)
GluCls (1)
Adiponectin receptor (1)
stilbene oxidase (1)
Stemness kinase (1)
Annexin A (1)
Glutathione reductase (1)
TSH Receptor (1)
Taste receptor (1)
Apelin receptor (1)
RANKL/RANK (1)
N-Acetylglucosaminyltransferase (1)
Anion Exchanger (1)
lysosomal autophagy (1)
FKBP (1)
aconitase (1)
Neuropeptide W (1)
Somatostatin (1)
LHRH (1)
Fer/FerT kinase (1)
VDA (1)
Procollagen C Proteinase (1)
GPCR19 (1)
FABP (1)
Ligands for Target Protein for PROTAC (1)
Fas/FasL (1)
Thioredoxin (1)
CPT (1)
OCT (1)
RAR/RXR  (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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