52
12
34
1
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21919 | UCF 101 | Apoptosis | |
UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells. | |||
T76371 | Tumor targeted pro-apoptotic peptide | ||
Tumor targeted pro-apoptotic peptide (CNGRC-GG-D(KLAKLAK)2) is an anti-tumor peptide. Tumor targeted pro-apoptotic peptide disrupts mitochondrial membranes and promotes apoptosis , showing anticancer activity in mice [1]... | |||
T23861 | CAY10526 | CAY-10526,BTH,CAY 10526 | Prostaglandin Receptor |
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway. | |||
T12870 | SCH79797 dihydrochloride | Apoptosis , Others , Protease-activated Receptor | |
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects. | |||
T77662 | DJ4 | Apoptosis | |
DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range. | |||
T13689 | Ethylene dimethanesulfonate | Apoptosis | |
Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs. Ethylene dimethanesulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. | |||
T4212 | XMU-MP-1 | Hippo pathway | |
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2. | |||
T12644L | (S)-Thalidomide | (S)-(-)-Thalidomide | Apoptosis |
(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-isomer of Thalidomide with immunomodulatory, anti-inflammatory, anticancer, anti-angiogenic and pro-apoptotic activities, and is used in the study of leprosy erythema nodosu... | |||
T77571 | Bcl-B inhibitor 1 | Apoptosis , BCL | |
Bcl-B inhibitor 1 is a Bcl-B inhibitor with antitumor activity that binds to and inactivates pro-apoptotic proteins in the BH3 structural domain. | |||
T9726 | 2’-OMe-Guanosine | Apoptosis , Nucleoside Antimetabolite/Analog | |
2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect. | |||
T77332 | TV 3279 | BCL , PKC | |
TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SOD, and to block the nuclear translocation of the pro-apopto... | |||
T70388 | (S)-Enitociclib | VIP152 | CDK |
(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that induces complete regression of MYC+ lymphomas by inhibiting RNA polymerase II-mediated transcription of anti-apoptotic and pro-survival proteins. | |||
T10827 | CK2/ERK8-IN-1 | TMCB | Apoptosis , ERK , Casein Kinase , Pim , DYRK |
CK2/ERK8-IN-1 (TMCB) is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 µM) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 µM, 11.9 µM, and 15.25... | |||
T31020 | CP 461 | OSI 461,UNII-68OJX9I7DT,CP-461,CP461 | Apoptosis , PDE |
CP 461 (UNII-68OJX9I7DT), a specific PDE2A inhibitor, is a novel pro-apoptotic compound that inhibits cyclic GMP phosphodiesterase but not cyclooxygenase-1 or -2. CP 461 inhibits the growth of a variety of human tumor ce... | |||
T10706 | CCI-006 | Mitochondrial Metabolism | |
CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein r... | |||
T2129 | Zaprinast | PDE | |
Zaprinast is a cGMP-selective phosphodiesterase (PDE) inhibitor and a GPR35 agonist. It has a strong activating effect on rat GPR35 and a certain activating effect on human GPR35. It reduces vascular remodeling through a... | |||
T21911 | Rilmenidine hemifumarate | Rilmenidine (hemifumarate),S-3341 hemifumarate | Apoptosis , Imidazoline Receptor |
Rilmenidine hemifumarate (S-3341 hemifumarate) is a novel, orally active and selective I1 imidazoline receptor and α2-adrenoceptor agonist that induces autophagy, regulates the proliferation of leukaemia cells, stimulate... | |||
T60202 | MMRi62 | 7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol | Ferroptosis |
MMRi62 (7-[(2,3-dichlorophenyl)-(pyridin-2-ylamino)methyl]quinolin-8-ol), a ferroptosis inducer targeting MDM2-MDM4 (negative regulators of tumor suppressor p53). MMRi62 shows a P53-independent pro-apoptotic activity aga... | |||
T36013 | Lysophosphatidylcholines | Lyso-Lecithins (egg) | |
Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 position by phospholipase A2 (PLA2) or by lecithin-cholesterol acyltranferase (LCAT), which transfer... | |||
T34335 | RM-133 | RM133 | |
RM-133 is a promising pro-apoptotic agent which shows activity on various cancer cell lines. | |||
TP1611 | Bim BH3, Peptide IV | ||
This Bim peptide belongs to the pro-apoptotic group of the Bcl-2 family of proteins. | |||
T36901 | Pelcitoclax | ||
Pelcitoclax (APG-1252) is a powerful inhibitor of the Bcl-2 and Bcl-xl proteins, displaying significant antineoplastic and pro-apoptotic properties[1]. | |||
T26789 | BH3I-2' | BH3I2',BH3I 2' | |
BH3I-2' is a cell-permeable BH3 mimetic. BH3I-2' induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the in... | |||
T72906 | [D-Leu-4]-OB3 | ||
-OB3 inhibits expressions of pro-inflammatory, proliferative and metastatic genes and PD-L1 expression. -OB3 stimulates expression of pro-apoptotic genes . | |||
T29060 | UNBS-1450 | UNBS 1450,UBS1450,UBS-1450,UBS 1450 | |
UNBS-1450 is a sodium channel antagonist. UNBS-1450 is a hemi-synthetic cardenolide derived from 2″-oxovorusharin, it is effective against various cancer cell types with an excellent differential toxicity. At low nanomol... | |||
T80038 | Bim BH3 | ||
Bim BH3 is a bioactive peptide that belongs to the pro-apoptotic Bcl-2 family of proteins. | |||
TP1718 | Bim BH3, Peptide IV TFA (721885-31-0 free base) | Bim BH3, Peptide IV TFA | |
Bim BH3, Peptide IV TFA is a 26-site residue of BH3 protein Bim, belonging to the pro-apoptotic group of bcl-2 protein family. | |||
T68027 | (Z/E)-cp-461 free base | ||
CP-461 is an orally bioavailable second-generation selective apoptotic antineoplastic drug (SAAND) and analog of the nonsteroidal anti-inflammatory drug (NSAID) sulindac, with potential pro-apoptotic and antineoplastic a... | |||
T35270 | YO-Pro 1 | YO-Pro1,YO-Pro-1 | |
YO-Pro 1, a cyanine dye consisting of benzoxazole and quinoline rings connected by a linker, is almost nonfluorescent in water, but its fluorescence is greatly enhanced after intercalation in double-stranded DNA, forming... | |||
T11534L | Haemanthamine hydrochloride (466-75-1 free base) | Haemanthamine hydrochloride | Others |
Haemanthamine hydrochloride is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-ap... | |||
T76073 | BH3 hydrochloride | ||
BH3 hydrochloride, a BBB penetrated peptide, provoke apoptosis either by direct activation of pro-apoptotic Bax/Bak or by neutralizing anti-apoptotic Bcl-2 proteins (Bcl-2, Bcl-XL , Bcl-w , Mcl-1 and A-1) via their BH3 d... | |||
T69296 | PHA-680626 | ||
PHA-680626 is a potent and selective PLK inhibitor. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of bot... | |||
T76030 | Bim BH3, Peptide IV TFA | ||
Bim BH3, Peptide IV TFA is a 26-residue peptide from BH3-only protein Bim , which belongs to the pro-apoptotic group of the Bcl-2 family of proteins [1] [2] . | |||
T71301 | Opaganib HCl | ||
ABC294640, also known as Opaganib, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitivel... | |||
T76315 | HKPao | ||
HKPao (Hunter-killer peptide ao) is a biologically active peptide . HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles [1] . | |||
T70008 | Bomedemstat ditosylate | ||
Bomedemstat, also known as IMG-7289, is a lysine-specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity. Bomedemstat may be useful in the treatment of acute myeloid leukaemia, myelodysplastic syndro... | |||
T63757 | Bcl-2-IN-9 | ||
Bcl-2-IN-9 is a novel, pro-apoptotic, low cytotoxic Bcl-2 inhibitor (IC50: 2.9 μM). Bcl-2-IN-9 downregulates Bcl-2 expression, induces apoptosis in cancer cells, and exhibits high selectivity for leukemia cells. | |||
TP1965 | Parstatin(human) | Parstatin (human) | |
Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation... | |||
TP1966 | Parstatin(mouse) | Parstatin (mouse) | |
Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 μM), and induces cell cycle arrest. Promotes activatio... | |||
T28874 | SU11652 | SU-11652,SU 11652 | |
SU11652 is a potent cell-permeable pyrrole-indolinone compound. SU11652 acts as an ATP-competitive tyrosine kinase receptor and angiogenic inhibitor with greater selectivity for PDGFR-β (PDGFRβ, IC50 = 3 nM), Flk-1 (VEGF... | |||
T38042 | Resolvin D4 | Resolvin D4,RvD4 | |
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid . [1] It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreat... | |||
T72570 | Antitumor agent-83 | ||
Antitumor agent-83 is an activator of pro-apoptotic protein BAX and has significant anti-proliferation effect on tumor cells. Antiumor agent-83 mediates cell Apoptosis by inducing the conformational activation of BAX and... | |||
T37166 | RCTR1 | ||
Resolvin conjugate in tissue regeneration 1 (RCTR1) is a specialized pro-resolving mediator (SPM) biosynthesized from docosahexaenoic acid by isolated human macrophages and apoptotic polymorphonuclear (PMN) neutrophils.1... | |||
T37379 | Protectin D1 | ||
Protectin D1 is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to protectin D1 enzymatically. Protectin D1 increases phag... | |||
T68656 | Brivudine monophosphate | ||
Brivudine monophosphate is a phosphate ester of Brivudine. Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bro... | |||
T83751 | PUMA BH3 (human) TFA | ||
PUMA BH3, a peptide that includes the BH3 domain from the p53-upregulated modulator of apoptosis (PUMA) and activates the pro-apoptotic protein Bak, demonstrates binding affinity to Bak with dissociation constants (Kds) ... | |||
T38043 | Resolvin E4 | ||
Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acid by 15-lipoxygenase (15-LO)via15(S)-HpEPE and 15S-hydroxy, 5S-HpEPE inte... | |||
T79919 | S-Adenosyl-L-methionine (1,4-butanedisulfonate) | Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate) | Endogenous Metabolite |
S-Adenosyl-L-methionine (SAMe) 1,4-butanedisulfonate functions as an orally active methyl group donor and serves as a dietary supplement known for its significant antidepressant properties. Additionally, it plays anti-pr... | |||
T80226 | R8 Bid BH3 | ||
r8 Bid BH3, a biologically active peptide, is a pro-apoptotic member of the "BH3-only" subset within the BCL-2 family proteins, pivotal in regulating apoptosis. This compound exhibits lethality towards Bcl-2-expressing h... | |||
T64158 | Nenocorilant | ||
Nenocorilant (Relacorilant) is an orally active glucocorticoid receptor (GR) antagonist (Ki: 0.15 nM). Nenocorilant can be used to study tumours. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8193 | α-Thujone | Thujone,ALPHA-(-)-THUJONE | Apoptosis , Reactive Oxygen Species , GABA Receptor , AChR , Parasite , Autophagy |
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM. | |||
T13903 | Stearoylethanolamide | N-(2-Hydroxyethyl)octadecanamide | Apoptosis |
Stearoylethanolamide(N-(2-Hydroxyethyl)octadecanamide) is a cannabinoid compound present in the brains of humans, rats, and mice with pro-apoptotic activity. | |||
T3395 | Timosaponin AIII | Filiferin B,AneMarsaponin A3,Timosaponin A3 | AChE , mTOR |
Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC... | |||
T5679 | (E)-Ferulic acid | trans-Ferulic acid,(E)-Coniferic acid | BCL , Ferroptosis , Wnt/beta-catenin , Endogenous Metabolite |
(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pr... | |||
T36715 | Tetrac | Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid | Apoptosis , EGFR |
Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac... | |||
TCS2170 | 2,5-Dihydroxyacetophenone | Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP | ERK , NF-κB , Tyrosinase |
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK... | |||
T13864 | Resolvin D1 | RvD1 | Others |
Resolvin D1 is an endogenous pro-resolving mediator of inflammation, blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagoc... | |||
T11534 | Haemanthamine | Others | |
Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiv... | |||
TMA1743 | Ergosterol peroxide | ERK , VEGFR , p38 MAPK , Wnt/beta-catenin , Akt , JAK , CDK , JNK , STAT , Antifection | |
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inhibiting pAKT and c-Myc and activating pr... | |||
TN1543 | Cynaropicrin | IL Receptor , Others , TNF | |
Cynaropicrin is a potent activator of the AhR-Nrf2-Nqo1 pathway, and could therefore be applied to prevention of UVB-induced photo aging; it may be a potential anticancer agent against some leukocyte cancer cells such as... | |||
T73813 | Haemanthamine hydrochloride | ||
Haemanthamine hydrochloride is a crinine-type alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. Haemanthamine hydrochloride targets ribosomal that inhibits protein biosynthesis during the ... | |||
TMA0918 | Neochamaejasmine A | Caspase | |
Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02700 | BCL2 Protein, Human, Recombinant (His) | Human | E. coli |
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a... | |||
TMPY-04572 | MKK4 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is... | |||
TMPY-01356 | S100A8 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation.... | |||
TMPY-00731 | Cathepsin B Protein, Human, Recombinant (His) | Human | HEK293 |
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas... | |||
TMPY-00834 | IGF1R/CD221 Protein, Human, Recombinant (His) | Human | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPK-00533 | TYRO3 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew mac... | |||
TMPK-00901 | TYRO3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew mac... | |||
TMPY-01561 | PIG3 Protein, Human, Recombinant (His) | Human | E. coli |
Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of ca... | |||
TMPY-03974 | Bim Protein, Human, Recombinant (His) | Human | E. coli |
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. ... | |||
TMPH-00958 | AHR Protein, Human, Recombinant (His) | Human | E. coli |
Thiol protease that plays a key role in programmed cell death by acting as a molecular switch for apoptosis, necroptosis and pyroptosis, and is required to prevent tissue damage during embryonic development and adulthood... | |||
TMPH-00495 | Lutropin subunit beta Protein, Canine, Recombinant (His) | Canine | E. coli |
Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic pro... | |||
TMPJ-00584 | Bc1-w Protein, Human, Recombinant (His) | Human | E. coli |
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing thre... | |||
TMPY-03434 | BMF Protein, Human, Recombinant (His) | Human | E. coli |
BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF... | |||
TMPJ-01066 | CYCS Protein, Human, Recombinant (His) | Human | E. coli |
Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as... | |||
TMPY-02578 | DKKL1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Dickkopf-like 1 (DKKL1) or soggy 1, is a glycoprotein unique to mammals that is expressed primarily in developing spermatocytes and localized in the acrosome of mature sperm. It is also expressed in the trophectoderm / p... | |||
TMPH-03026 | CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-m... | |||
TMPY-02065 | BID Protein, Mouse, Recombinant (His & GST) | Mouse | E. coli |
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro... | |||
TMPH-00904 | Adenylate kinase 7 Protein, Human, Recombinant (His) | Human | Baculovirus |
Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-... | |||
TMPY-02027 | BID Protein, Human, Recombinant | Human | E. coli |
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro... | |||
TMPY-04930 | Notch 2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
NOTCH2 (Notch Receptor 2) is a Protein Coding gene. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of dev... | |||
TMPY-04109 | Galectin-7 Protein, Human, Recombinant (His) | Human | E. coli |
LGALS7, also known as Galectin-7, is a member of the galectins family. The galectins are a family of beta-galactoside-binding proteins. There are at least 14 identified members of this family. Galectins share similaritie... | |||
TMPH-01478 | HIST1H2AG Protein, Human, Recombinant (His) | Human | E. coli |
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25... | |||
TMPY-02774 | Galectin-7 Protein, Human, Recombinant (GST) | Human | E. coli |
LGALS7, also known as Galectin-7, is a member of the galectins family. The galectins are a family of beta-galactoside-binding proteins. There are at least 14 identified members of this family. Galectins share similaritie... | |||
TMPH-01621 | BRCC3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Through... | |||
TMPH-02315 | XRCC5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negativel... | |||
TMPY-04455 | PKC iota Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr prote... | |||
TMPY-03556 | S100A8 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation.... | |||
TMPY-04503 | Cathepsin B Protein, Rat, Recombinant (His) | Rat | HEK293 |
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas... | |||
TMPH-00786 | BtuD Protein, Halobacterium salinarum, Recombinant (His) | Halobacterium salinarum | E. coli |
Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad spe... | |||
TMPY-02144 | Cathepsin B Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas... | |||
TMPY-04360 | IGF1R/CD221 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPH-02588 | COL12A1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways. Exhibits kinase activity-dependent functions that regulate cell death and kinase-independent scaffold fun... | |||
TMPY-06195 | IGF1R/CD221 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPY-06905 | IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... |
Cat No. | Product Name | ||
---|---|---|---|
L9000 | Apoptosis Compound Library | 1796 compounds | |
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; |