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DJ4
🥰Excellent
Catalog No. T77662Cas No. 1681020-24-5
DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.
DJ4
🥰Excellent
Catalog No. T77662Cas No. 1681020-24-5
DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $59 | In Stock | |
| 5 mg | $146 | In Stock | |
| 10 mg | $228 | In Stock | |
| 25 mg | $443 | In Stock | |
| 50 mg | $655 | In Stock | |
| 100 mg | $932 | In Stock | |
| 500 mg | $1,880 | In Stock |
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Purity:≥98%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range. |
| In vitro | In cellular functional assays, DJ4 inhibited migration of humanmelanoma, lung, pancreatic and breast cancer cells in a concentration-dependent manner. In live cellimaging over 20h by time-lapse microscopy, DJ4 (2.5 pM ) reduced the migration rate of lung-andbreast-cancer cells by 2.7 and 5.5 times compared to control cells respectively, DJ4 (5 pM) alsoinhibited invasion of MDA-MB-231 breast cancer cells by ~70%. Fluorescent microscopicobservation also revealed that inhibition of activity of these kinases, by DJ4, causes reduction instress fibers which leads to inhibition of cell contractility and migration.[1] |
| Molecular Weight | 348.42 |
| Formula | C19H16N4OS |
| Cas No. | 1681020-24-5 |
| Smiles | C(\C=1C=2C(NC1)=NC=CC2)=C/3\SC(NCCC4=CC=CC=C4)=NC3=O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 5.63 mg/mL (16.05 mM), Sonication is recommended.  | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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