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Biochemicals
- Autophagy
- Cell Cycle/Checkpoint
- Cytoskeletal Signaling
- Chromatin/Epigenetic
- Endocrinology/Hormones
- Hedgehog/Smoothened
- Angiogenesis
- DNA Damage/DNA Repair
- Apoptosis
- NF-κB
- Neuroscience
- MAPK
- Microbiology/Virology
- GPCR/G Protein
- TGF-beta/Smad
- Immunology/Inflammation
- Proteases/Proteasome
- Stem Cells
- Ubiquitination
- Oxidation-Reduction
- Membrane transporter/Ion channel
- PI3K/Akt/mTOR signaling
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- Wnt/beta-catenin
- JAK/STAT signaling
- Tyrosine Kinase/Adaptors
- TLR
- PARP
- Antibody-drug Conjugate/ADC Related
- Focused Bioactive LibrariesApproved Drug LibraryFDA-Approved Drug LibraryFDA-Approved & Pharmacopeia Drug LibraryClinical Compound LibraryPreclinical Compound LibraryBioactive Compound LibraryTarget-Focused Phenotypic Screening LibraryReFRAME Related LibraryEpigenetics Compound LibraryCytoskeletal Signaling Pathway Compound LibraryTranscription Factor-Targeted Compound LibraryGPCR Compound LibraryIon Channel Inhibitor LibraryEndocrinology-Hormone Compound LibraryJAK-STAT Compound LibraryNF-κB Signaling Compound LibraryDNA Damage & Repair Compound LibraryUbiquitination Compound LibraryFerroptosis Compound LibraryCuproptosis Compound LibraryKinase Inhibitor LibraryAnti-Cancer Compound LibraryAnti-Bacterial Compound LibraryAnti-Cardiovascular Disease Compound LibraryCNS-Penetrant Compound LibraryAnti-Viral Compound LibraryAnti-Neurodegenerative Disease Compound LibraryPeptide Compound Library
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- PROTAC
- E3 Ligase Ligand-Linker Conjugate
- Ligand for E3 Ligase
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- PROTAC Selection
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- Target Protein Ligand-Linker Conjugate
- dyes
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- ALK
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- EGFR
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- Ferroptosis
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- OXPHOS
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- DUB
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- IRE1
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- Nucleoside Antimetabolite/Analog
- PD-1/PD-L1
- PLK
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- Serine/threonin kinase
- Wee1
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- DNA Methyltransferase
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- HDAC
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- Histone Acetyltransferase
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- HuR
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- PAD
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- Pim
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- Arp2/3 Complex
- Bcr-Abl
- Dynamin
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- Gap Junction Protein
- HSP
- Integrin
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- Myosin
- PAK
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- BMI-1
- CRISPR/Cas9
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- Thyroid hormone receptor(THR)
- 5-HT Receptor
- Adenosine Receptor
- Adiponectin receptor
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- Amylin Receptor
- Annexin A
- Apelin receptor
- Arrestin
- Bombesin Receptor
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- cAMP
- Cannabinoid Receptor
- CaSR
- CGRP Receptor
- cholecystokinin
- CRFR
- CXCR
- Dopamine Receptor
- EBI2/GPR183
- Endothelin Receptor
- GHSR
- Glucagon Receptor
- GNRH Receptor
- GPCR19
- GPR
- GRK
- GTPase
- Guanylate cyclase
- Hedgehog/Smoothened
- Histamine Receptor
- Kisspeptin
- Leukotriene Receptor
- LPA Receptor
- LPL Receptor
- Melanin-concentrating Hormone Receptor (MCHR)
- Melanocortin Receptor
- Melatonin Receptor
- Motilin Receptor
- Neurokinin receptor
- Neuropeptide W
- Neuropeptide Y Receptor
- Neurotensin Receptor
- Opioid Receptor
- OX Receptor
- Oxytocin Receptor
- P2Y Receptor
- PACAP
- PAFR
- Prostaglandin Receptor
- Protease-activated Receptor
- Ras
- RXFP receptor
- S1P Receptor
- SGLT
- Sigma receptor
- Somatostatin
- TSH Receptor
- Vasopressin Receptor
- AhR
- AIM2
- Antiviral
- Arginase
- Aryl Hydrocarbon Receptor
- CCR
- CD38
- CD73
- Cell wall
- cGAS
- Complement System
- COX
- CXCR
- Cytokine release
- FKBP
- FLAP
- Galectin
- gp120/CD4
- Histamine Receptor
- IFNAR
- IL Receptor
- Immunology/Inflammation related
- Interleukin
- IRAK
- LTR
- MALT
- MRP
- MyD88
- NADPH-oxidase
- NO Synthase
- NOD
- NOD-like Receptor (NLR)
- NOS
- Nrf2
- PD-1/PD-L1
- PGE Synthase
- Prostaglandin Receptor
- Pyroptosis
- Reactive Oxygen Species
- ROS
- STING
- Thrombopoietin Receptor
- TLR
- EGFR
- HER
- JAK
- Pim
- STAT
- ERK
- JNK
- KLF
- KLF
- MAPK
- MEK
- MLK
- MNK
- p38 MAPK
- Raf
- Ras
- S6 Kinase
- TOPK
- ABC
- Anion Exchanger
- Aquaporin
- ATPase
- BCRP
- Calcium Channel
- CFTR
- Chloride channel
- CRM1
- GABA Receptor
- HCN Channel
- iGluR
- Monoamine Transporter
- Monocarboxylate transporter
- Na+/Ca2+ Exchanger
- Na-K-Cl cotransporter
- NPC1L1
- OAT
- OCT
- P2X Receptor
- P-gp
- Piezo Channel
- Potassium Channel
- Proton pump
- Sodium Channel
- TRP/TRPV Channel
- VDAC
- Acetyl-CoA Carboxylase
- aconitase
- Acyltransferase
- Adenosine deaminase
- AhR
- Amino Acids and Derivatives
- Aminopeptidase
- Amylase
- Angiotensin-converting Enzyme (ACE)
- ATP Citrate Lyase
- Calcium Channel
- Carbonic Anhydrase
- Casein Kinase
- CETP
- CPT
- Decarboxylase
- Dehydrogenase
- DHFR
- Drug Metabolite
- Endogenous Metabolite
- Epoxide Hydrolase
- FAAH
- FABP
- Factor Xa
- Fatty Acid Synthase
- FXR
- Glucokinase
- Glucosidase
- Glutathione Peroxidase
- Glycosidase
- GSNOR
- hCE
- Hexokinase
- HIF/HIF Prolyl-Hydroxylase
- HMG-CoA Reductase
- HSP
- Hydrogenase
- Hydroxylase
- IDO
- Indoleamine 2,3-Dioxygenase (IDO)
- Isocitrate Dehydrogenase (IDH)
- LDL
- Lipase
- Lipid
- Lipoxygenase
- Liver X Receptor
- MAGL
- MAO
- Mitochondrial Metabolism
- N-Acetylglucosaminyltransferase
- NADPH
- NAMPT
- NEDD8
- Neprilysin
- NUDIX hydrolase
- P450
- PAI-1
- PDE
- Phosphatase
- Phospholipase
- Phosphorylase
- PKM
- PPAR
- Procollagen C Proteinase
- Prolyl Endopeptidase (PREP)
- RAR/RXR
- Reactive Oxygen Species
- Reductase
- Retinoid Receptor
- ROR
- Serine/threonin kinase
- SGK
- Stearoyl-CoA Desaturase (SCD)
- stilbene oxidase
- Taste receptor
- Thioredoxin
- Transaminase
- Transferase
- transporter
- UGT
- Vitamin
- Xanthine Oxidase
- Antibacterial
- Antibiotic
- Antifection
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- CCR
- GluCls
- HBV
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- HIV Protease
- HSV
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- Integrase
- Parasite
- Reverse Transcriptase
- Ribosome
- RSV
- SARS-CoV
- Virus Protease
- 5-HT Receptor
- AAK1 (AP2 associated kinase 1)
- AChE
- AChR
- Adenosine Receptor
- Adenylyl cyclase
- Adrenergic Receptor
- BACE
- Beta Amyloid
- Beta-Secretase
- CaMK
- CGRP Receptor
- COX
- Dopamine Receptor
- FAAH
- GABA Receptor
- Gamma-secretase
- GluR
- GlyT
- Histamine Receptor
- Huntingtin
- iGluR
- Imidazoline Receptor
- MAO
- Melanocortin Receptor
- Monoamine Oxidase
- MT Receptor
- Neurokinin receptor
- Neuropeptide W
- Neuropeptide Y Receptor
- NMDAR
- NMU2R
- Norepinephrine
- Opioid Receptor
- OX Receptor
- P2X Receptor
- P2Y Receptor
- P-gp
- Serotonin Transporter
- IRAK
- IκB/IKK
- NF-κB
- NOD
- RANKL/RANK
- Reactive Oxygen Species
- RIP kinase
- advanced glycation end products
- CYP19A1
- Decarboxylase
- DprE1
- Fer/FerT kinase
- Others
- Platelet aggregation
- Progesterone Receptor
- Antioxidant
- CAT
- Free radical scavengers
- Glutathione reductase
- GPX
- GST
- Akt
- AMPK
- ATM/ATR
- DNA-PK
- GSK-3
- MELK
- mTOR
- PDK
- PI3K
- PI4K
- PTEN
- S6 Kinase
- SIK
- ATTECs
- AUTACs
- E3 Ligase Ligand-Linker Conjugate
- Ligand for E3 Ligase
- Ligands for Target Protein for PROTAC
- LYTACs
- Molecular Glues
- PROTAC Linker
- PROTACs
- SNIPERs
- Target Protein Ligand-Linker Conjugate
- Carboxypeptidase
- Caspase
- Cysteine Protease
- DPP-4
- Gamma-secretase
- Glutaminase
- HCV Protease
- HIV Protease
- MMP
- Prolyl Endopeptidase (PREP)
- Protease
- Proteasome
- Serine Protease
- Thrombin
- Tyrosinase
- Casein Kinase
- Gamma-secretase
- GSK-3
- Hedgehog/Smoothened
- Hippo pathway
- JAK
- Porcupine
- ROCK
- Smo
- STAT
- Stemness kinase
- TGF-beta/Smad
- Wnt/beta-catenin
- YAP
- ACK
- ALK
- Bcr-Abl
- BTK
- c-Fms
- c-Kit
- c-Met/HGFR
- c-RET
- CSF-1R
- Discoidin Domain Receptor (DDR)
- DYRK
- EGFR
- Ephrin Receptor
- FAK
- FGFR
- FLT
- Hck
- HER
- IGF-1R
- PDGFR
- PKA
- PYK2
- ROS Kinase
- Src
- Syk
- TAM Receptor
- Tie-2
- Trk receptor
- Tyrosine Kinases
- VEGFR
- DUB
- E1/E2/E3 Enzyme
- p97
- Proteasome
- PROTAC-Linker Conjugates for PAC
- Drug-Linker Conjugates for ADC
- Antibody-Drug Conjugates (ADCs)
- ADC Linker
- ADC Cytotoxin
- ADC Antibody
- General Bioactive Libraries
- Approved / Repurposing
- Characteristic Bioactive Libraries
- Disease Focused
- Target / Pathway Focused
- Natural Product Derivatives Libraries
- Natural Product Library for HTS
- Characteristic Natural Product Libraries
- TCM Natural Product Library
- Activity-classified Natural Product Library
- Structure-classified Natural Product Library
- Characteristic Fragment Libraries
- General Fragment Libraries
- Compound Libraries for HTS/HCS
- Tumor
- Anti-infective
- Cardiovascular disease
- Development and reproduction
- Digestive disorders
- Inflammation and immunity
- Metabolic diseases
- Neurological disorders
- Other Fields
- Alangiaceae
- Aquifoliaceae
- Cephalotaxaceae
- Costaceae
- Daphniphyllaceae
- Dioscoreaceae
- Eucommiaceae
- Ginkgoaceae
- Hippocastanaceae
- Illiciaceae
- Lycopodiaceae
- Moringaceae
- Myricaceae
- Myristicaceae
- Nelumbonaceae
- Nothofagaceae
- Nyssaceae
- Orobanchaceae
- Paeoniaceae
- Piperaceae
- Podocarpaceae
- Pteridaceae
- Resedaceae
- Sapindaceae
- Schisandraceae
- Stemonaceae
- Theaceae
- Other
- Alkaloids
- Coumarins
- Flavonoids
- Lignans
- Others
- Phenols
- Phenylpropanoids
- Quinones
- Saccharides and Glycosides
- Steroids
- Terpenoids
- Hematologic Malignancies Target Proteins
- Solid Tumors Target Proteins
- B Cell CD Proteins
- Cell Activation CD Proteins
- Cell Adhesion CD Proteins
- Cytokine Receptor CD Proteins
- Endothelial Cell CD Proteins
- Myeloid Cell CD Proteins
- NK/Non-lineage Cell CD Proteins
- Other CD Proteins
- Platelet CD Proteins
- T Cell CD Proteins
- Cytokines
- Epidermal Growth Factor Family, EGFs
- Growth Factors
- Others
- Hydrolases,EC 3
- Isomerases,EC 5
- Ligases or Synthetases,EC 6
- Lyases,EC 4
- Oxidoreductases,EC 1
- Transferases,EC 2
- Translocases,EC 7
- Butyrophilins
- Co-inhibitory Immune Checkpoint Proteins
- Co-stimulatory Immune Checkpoint Proteins
- Cell Adhesion Receptors
- Cytokines and Growth Factor Receptors
- Enzyme-Linked Receptors
- Fc Receptors
- G Protein-Coupled Receptors, GPCRs
- Ion Channel-Linked Receptors
- Nuclear Receptors
- Receptor Serine/Threonine Kinases
- Receptor Tyrosine Kinases
- Others
- Coronavirus (CoV) Proteins
- DENV Proteins
- EBOV Proteins
- HBV Proteins
- HCV Proteins
- HIV Proteins
- Influenza Proteins
- RSV Proteins
- Others
- Molecular Docking
- Virtual Screening
- Biomolecular Interaction
- Custom Synthesis
- AI-driven Ultra High-throughput Virtual Screening
Integrase
Retroviral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that integrates—forms covalent links between—its DNA (genetic information) into that of the host cell it infects.[citation needed] Retroviral INs are not to be confused with phage integrases (recombinases), such as λ phage integrase, as discussed in site-specific recombination.
Raltegravir
Cited
T2239L518048-05-0
Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.
- $38
Size
QTY
CitedRaltegravir potassium
T2239871038-72-1
Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
- $37
Size
QTY
Lucialdehyde B
TN4455480439-84-7
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines.
- $345
Size
QTY
Ganoderone A
TN1671873061-79-1
Ganoderone A exhibits potent inhibitory activity against herpes simplex virus.
- $820
Size
QTY
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