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Enzyme-Linked Receptors

Enzyme-Linked Receptors are transmembrane receptors, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side. Hence an enzyme-linked receptor is an integral membrane protein possessing both catalytic, and receptor functions. Most enzyme-linked receptors are receptor tyrosine kinase.They have two important domains, an extra-cellular ligand binding domain and an intracellular domain, which has a catalytic function,and a single transmembrane helix. The signaling molecule binds to the receptor on the outside of the cell and causes a conformational change on the catalytic function located on the receptor inside the cell.

HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
TMPY-01137
HER2 ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
  • $329
In Stock
Size
QTY
MERTK/Mer Protein, Mouse, Recombinant (His)
TMPK-01022
MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. MERTK Mer Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 53.38 kDa and the accession number is Q60805.
  • $418
In Stock
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QTY
EphA2 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06812
EphA2 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 60 kDa and the accession number is NP_034269.2.
  • $600
In Stock
Size
QTY
ROR1 Protein, Human, Recombinant, Biotinylated
TMPY-04986
ROR1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 42.8 kDa and the accession number is Q01973.
  • $383
In Stock
Size
QTY
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
  • $628
In Stock
Size
QTY
HER2/ERBB2 Protein, Human, Recombinant
TMPY-00167
HER2 ERBB2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 70 kDa and the accession number is P04626-1.
  • $504
In Stock
Size
QTY
TGFBR2 Protein, Human, Recombinant (His)
TMPY-05157
TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173.
  • $320
In Stock
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QTY
TIE2 Protein, Human, Recombinant (His)
TMPY-01064
TIE2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82 kDa and the accession number is AAA61139.1.
  • $255
In Stock
Size
QTY
AXL Protein, Human, Recombinant (His)
TMPY-01601
AXL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAB20305.1.
  • $136
In Stock
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QTY
HER2/ERBB2 Protein, Human, Recombinant (His)
TMPJ-00778
HER2 ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
  • $75
In Stock
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QTY
TGFBR2 Protein, Human, Recombinant (hFc)
TMPY-05508
TGFBR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is P37173.
  • $398
7-10 days
Size
QTY
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
TMPY-00614
BMPR1A ALK-3 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is A0A8C0S7K5.
  • $398
7-10 days
Size
QTY
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated
TMPY-05810
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P37173.
  • $383
7-10 days
Size
QTY
ALK-5 Protein, Human, Recombinant (hFc)
TMPY-05771
ALK-5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.87 kDa and the accession number is P36897-1.
  • $357
7-10 days
Size
QTY
ALK-1 Protein, Cynomolgus, Recombinant (His)
TMPY-00310
ALK-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is A0A2K5WXU2.
  • $600
7-10 days
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ALK-4/ACVR1B Protein, Rhesus, Recombinant (hFc)
TMPY-03100
ALK-4 ACVR1B Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.2 kDa and the accession number is I2CYX8.
  • $600
7-10 days
Size
QTY
ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05603
ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.2 kDa and the accession number is Q01973.
  • $462
7-10 days
Size
QTY
PDGFRA Protein, Mouse, Recombinant (His)
TMPY-05787
PDGFRA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.87 kDa and the accession number is P26618-2.
  • $357
7-10 days
Size
QTY
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
TMPY-04956
HER3 ERBB3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1.
  • $256
In Stock
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TIE2 Protein, Mouse, Recombinant (hFc)
TMPY-01954
TIE2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 107.7 kDa and the accession number is B1AWS8.
  • $600
7-10 days
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PDGFRA Protein, Mouse, Recombinant (hFc)
TMPY-05789
PDGFRA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.15 kDa and the accession number is P26618-2.
  • $357
7-10 days
Size
QTY
FLT1 Protein, Human, Recombinant (hFc)
TMPY-00119
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
  • $398
7-10 days
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RYK Protein, Human, Recombinant (hFc)
TMPY-05550
RYK Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is P34925-1.
  • $357
7-10 days
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TIE2 Protein, Rhesus, Recombinant (His)
TMPY-05049
TIE2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is G7NFP9.
  • $600
7-10 days
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HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05753
HER3 ERBB3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1.
  • $306
7-10 days
Size
QTY
HER3/ERBB3 Protein, Rat, Recombinant (hFc)
TMPY-03023
HER3 ERBB3 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.5 kDa and the accession number is A6KSF8.
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    EphB3 Protein, Mouse, Recombinant (His)
    TMPY-01784
    EphB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P54754.
    • $904
    7-10 days
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    QTY
    EphA4 Protein, Mouse, Recombinant (His)
    TMPY-01778
    EphA4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is Q03137-1.
    • $904
    7-10 days
    Size
    QTY
    FGFR2 Protein, Mouse, Recombinant (His)
    TMPY-03389
    FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is AAA39377.1.
    • $600
    7-10 days
    Size
    QTY
    BMPRIB Protein, Human, Recombinant (hFc)
    TMPY-03362
    BMPRIB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.7 kDa and the accession number is O00238-1.
    • $904
    7-10 days
    Size
    QTY
    DDR1 Protein, Rat, Recombinant (hFc)
    TMPY-03541
    DDR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.9 kDa and the accession number is Q6MG19.
    • $600
    7-10 days
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    QTY
    ACVR2B Protein, Cynomolgus, Recombinant (His)
    TMPY-03827
    ACVR2B Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa.
    • $904
    7-10 days
    Size
    QTY
    c-Kit Protein, Human, Recombinant (aa 50-190, His)
    TMPY-03567
    c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.9 kDa and the accession number is P10721-1.
    • $700
    7-10 days
    Size
    QTY
    HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST)
    TMPY-04379
    HGFR c-Met Protein, Human, Recombinant (aa 956-1390, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.8 kDa and the accession number is P08581-1.
    • $498
    7-10 days
    Size
    QTY
    BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)
    TMPY-04367
    BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.3 kDa and the accession number is O00238-1.
    • $498
    7-10 days
    Size
    QTY
    ROR1 Protein, Human, Recombinant (hFc)
    TMPY-04068
    ROR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69 kDa and the accession number is Q01973.
    • $222
    7-10 days
    Size
    QTY
    ACVR2B Protein, Cynomolgus, Recombinant (hFc)
    TMPY-03925
    ACVR2B Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.3 kDa and the accession number is G7MJ10.
    • $904
    7-10 days
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    Mer Protein, Human, Recombinant (His & GST)
    TMPY-04363
    Mer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 62 kDa and the accession number is Q12866.
    • $498
    7-10 days
    Size
    QTY
    EphA4 Protein, Human, Recombinant (aa 570-986, His & GST)
    TMPY-04485
    EphA4 Protein, Human, Recombinant (aa 570-986, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is P54764.
    • $498
    7-10 days
    Size
    QTY
    c-Kit Protein, Human, Recombinant (aa 540-972, His & GST)
    TMPY-04564
    c-Kit Protein, Human, Recombinant (aa 540-972, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.8 kDa and the accession number is P10721-2.
    • $398
    7-10 days
    Size
    QTY
    TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST)
    TMPY-04575
    TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.2kDa and the accession number is Q02858.
    • $398
    7-10 days
    Size
    QTY
    p38 gamma/MAPK12 Protein, Human, Recombinant
    TMPY-04430
    p38 gamma MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
    • $498
    7-10 days
    Size
    QTY
    p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)
    TMPY-04429
    p38 gamma MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
    • $498
    7-10 days
    Size
    QTY
    TrkA Protein, Cynomolgus, Recombinant (His)
    TMPY-06967
    TrkA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.95 kDa and the accession number is XP_005541454.3.
    • $600
    7-10 days
    Size
    QTY
    HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated
    TMPY-06660
    HER3 ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.92 kDa and the accession number is XP_001113953.2.
    • $600
    7-10 days
    Size
    QTY
    c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPY-06656
    c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 58.50 kDa and the accession number is P10721-2.
    • $600
    7-10 days
    Size
    QTY
    HGFR/c-Met Protein, Cynomolgus, Recombinant (His)
    TMPK-00499
    c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. HGFR c-Met Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 32.5 kDa (α chain) and 69.9 kDa (β chain) and the accession number is A0A2K5UM36.
    • $487
    7-10 days
    Size
    QTY
    FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
    TMPK-00384
    FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
    • $347
    7-10 days
    Size
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