Shopping Cart

Remove All

Your shopping cart is currently empty

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

Resource Download

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

Catalog No. TMPJ-00333

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
10 μg	$140	7-10 days
50 μg	$423	7-10 days
500 μg	$2,120	7-10 days
1 mg	$3,170	7-10 days

Bulk & Custom

Add to Cart

Questions

Biological Description

Description	TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q62312
Synonyms	Transforming growth factor-β receptor type II,TbetaR-II,TGF-β type II receptor,TβR-II,TGFR-2,TGF-beta receptor type II,Transforming growth factor-beta receptor type II,TGF-beta type II receptor,TGF-β receptor type II,Tgfbr2,TGF-beta receptor type-2,TGF-β receptor type-2
Amino Acid	Ile24-Asp184
Construction	Ile24-Asp184
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	60-75 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI), TGF-β receptor type II (TGF-β-RII), and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.