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advanced glycation end products

Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars. They are a bio-marker implicated in aging and the development, or worsening, of many degenerative diseases, such as diabetes, atherosclerosis, chronic kidney disease, and Alzheimer's disease.

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Azeliragon
T2507603148-36-3
Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-moderate Alzheimer_acute_s disease (AD).
  • $33
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FPS-ZM1
T3259945714-67-0
FPS-ZM1 is a high-affinity, RAGE-specific inhibitor that obstructs Aβ binding to the V domain of RAGE.
  • $43
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TargetMol | Citations Cited
Ipriflavone
T030935212-22-7
Ipriflavone (Osteofix) (Osteofix) is a feed additive and a catabolic agent. It is used to inhibit bone resorption.
  • $42
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TargetMol | Citations Cited
4'-Methoxyresveratrol
T571633626-08-3
4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a natural product from the roots of *Rheum palmatum* L., with significant hypoglycemic, anti-inflammatory, and antioxidant effects. 4'-Methoxyresveratrol alleviates AGE-induced inflammation by suppressing RAGE-mediated MAPK NF-κB signaling pathway and NLRP3 inflammasome activation.
  • $39
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TargetMol | Inhibitor Sale