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4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a natural product from the roots of *Rheum palmatum* L., with significant hypoglycemic, anti-inflammatory, and antioxidant effects. 4'-Methoxyresveratrol alleviates AGE-induced inflammation by suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $39 | In Stock | |
5 mg | $88 | In Stock | |
10 mg | $148 | In Stock | |
25 mg | $265 | In Stock | |
50 mg | $389 | In Stock | |
100 mg | $568 | In Stock | |
500 mg | $1,180 | In Stock |
Description | 4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a natural product from the roots of *Rheum palmatum* L., with significant hypoglycemic, anti-inflammatory, and antioxidant effects. 4'-Methoxyresveratrol alleviates AGE-induced inflammation by suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation. |
In vitro | 4'-Methoxyresveratrol significantly abated the activation of NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome including NLRP3 and cleaved caspase-1 and reduced the secretion of mature IL-1β. The anti-inflammatory effect of 4'-Methoxyresveratrol is mainly through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation. 4'-Methoxyresveratrol could be a novel therapeutic agent for inflammation-related diseases. |
Alias | 4'-O-Methylresveratrol |
Molecular Weight | 242.27 |
Formula | C15H14O3 |
Cas No. | 33626-08-3 |
Smiles | COc1ccc(\C=C\c2cc(O)cc(O)c2)cc1 |
Relative Density. | 1.252 |
Storage | keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (247.66 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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