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ACK

In molecular biology, acetate kinase , which is predominantly found in micro-organisms, facilitates the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation. Short-chain fatty acids (SCFAs) play a major role in carbon cycle and can be utilized as a source of carbon and energy by bacteria.

Vemurafenib
T2382918504-65-1
Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma.
  • $50
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TargetMol | Citations Cited
GNF-7
T3196839706-07-9
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
  • $37
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AIM-100
T5092873305-35-2
AIM-100 is a Ack1 inhibitor (IC50: 24 nM).
  • $42
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TargetMol | Inhibitor Sale
AZ7550
T135641421373-99-0
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
  • $133
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KRCA-0008
T26411472795-20-2
KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.
  • $39
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