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p97

p97 also known as VCP ( Cdc48 in yeast) is a hexameric ATPase of the AAA family which disassembles SNARE proteins after membrane fusion. It is involved in a fusion of homotypic membranes, protein degradation, and activation of membrane-bound transcription factors.
Cat No. product name
T1969 DBEQ DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.
T6594 MNS MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
T1853 NMS-873 NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.
T12114 MSC1094308 MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.
T4684 ML241 hydrochloride ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-r...
T3164 ML241 ML241 is a potent and selective inhibitors of p97 ATPase.
T3535 ML240 ML240 is a selective, ATP-competitive p97 inhibitor.
T6796 CB-5083 CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).
DBEQ
T1969
DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.
MNS
T6594
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
NMS-873
T1853
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.
MSC1094308
T12114
MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.
ML241 hydrochloride
T4684
ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-r...
ML241
T3164
ML241 is a potent and selective inhibitors of p97 ATPase.
ML240
T3535
ML240 is a selective, ATP-competitive p97 inhibitor.
CB-5083
T6796
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).