p97|Targetmol

p97

p97 also known as VCP ( Cdc48 in yeast) is a hexameric ATPase of the AAA family which disassembles SNARE proteins after membrane fusion. It is involved in a fusion of homotypic membranes, protein degradation, and activation of membrane-bound transcription factors.

Cat No.	product name
T1853	NMS 873	NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.
T1969	DBEQ	DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.
T3535	ML240	ML240 is a selective, ATP-competitive p97 inhibitor.
T6796	CB-5083	CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).
T3852	Rhodiosin	Rhodiosin is a compound with antioxidant activity.
T4684	ML241 hydrochloride	ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-...
T12114	MSC1094308	MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.

Cat No.

product name

T1853

NMS 873

NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.

T1969

DBEQ

DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.

T3535

ML240

ML240 is a selective, ATP-competitive p97 inhibitor.

T6796

CB-5083

CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).

T3852

Rhodiosin

Rhodiosin is a compound with antioxidant activity.

T4684

ML241 hydrochloride

ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-...

T12114

MSC1094308

MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.

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