p97

p97 also known as VCP ( Cdc48 in yeast) is a hexameric ATPase of the AAA family which disassembles SNARE proteins after membrane fusion. It is involved in a fusion of homotypic membranes, protein degradation, and activation of membrane-bound transcription factors.

Cat No.	product name
T1969	DBEQ	DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.
T6594	MNS	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
T1853	NMS-873	NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.
T12114	MSC1094308	MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.
T4684	ML241 hydrochloride	ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-r...
T3164	ML241	ML241 is a potent and selective inhibitors of p97 ATPase.
T3535	ML240	ML240 is a selective, ATP-competitive p97 inhibitor.
T6796	CB-5083	CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).

Cat No.

product name

T1969

DBEQ

DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.

T6594

MNS

MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.

T1853

NMS-873

NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.

T12114

MSC1094308

MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.

T4684

ML241 hydrochloride

ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-r...

T3164

ML241

ML241 is a potent and selective inhibitors of p97 ATPase.

T3535

ML240

ML240 is a selective, ATP-competitive p97 inhibitor.

T6796

CB-5083

CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).