p97

p97 also known as VCP ( Cdc48 in yeast) is a hexameric ATPase of the AAA family which disassembles SNARE proteins after membrane fusion. It is involved in a fusion of homotypic membranes, protein degradation, and activation of membrane-bound transcription factors.

Cat. No.	Product name	CAS No.	Purity
T3164	ML241	1346528-06-0	98%
ML241 is a potent and selective inhibitors of p97 ATPase.
T12114	MSC1094308	2219320-08-6	98%
MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.
T1969	DBEQ	177355-84-9	98%
DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.
T4684	ML241 hydrochloride	2070015-13-1	98%
ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-r...
T1853	NMS-873	1418013-75-8	98%
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor.
T60193	CB-5339	1863952-15-1	98%
p97-IN-1 is a potent inhibitor of p97 with an IC 50 <30 nM [1].
T6594	MNS	1485-00-3	98%
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
T3535	ML240	1346527-98-7	98%
ML240 is a selective, ATP-competitive p97 inhibitor.
T6796	CB-5083	1542705-92-9	98%
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T3164

ML241

1346528-06-0

98%

ML241 is a potent and selective inhibitors of p97 ATPase.

T12114

MSC1094308

2219320-08-6

98%

MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase.

T1969

DBEQ

177355-84-9

98%

DBeQ(JRF-12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.

T4684

ML241 hydrochloride

2070015-13-1

98%

ML241 is a potent and selective inhibitors of p97 ATPase.ML241 inhibits degradation of a p97-dependent but not a p97-independent proteasome substrate in a dual-r...

T1853

NMS-873

1418013-75-8

98%