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Peptides

Peptides are short chains of between two and fifty amino acids, linked by peptide bonds. Chains of less than ten or fifteen amino acids are called oligopeptides, and include dipeptides, tripeptides, and tripeptides. A polypeptide is a longer, continuous, and unbranched peptide chain of up to fifty amino acids. Hence, peptides fall under the broad chemical classes of biological oligomers and polymers, alongside nuclei acids, oligosaccharides, polysaccharides, and others. Targetmol provides more than 1000 polypeptide products, including pharmaceutical peptides, active peptides, peptide hormones, amino acid derivatives, and label peptides for scientific research only. We ensure quality by performing comprehensive analytical testing for our peptides (HPLC and LC-MS), stability testing and activity testing. Quality inspection results can be provided for customers.

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D-GsMTx4 TFA
T37697L
D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective stretch-activated channels (SACs), and attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglia reactivity. toxicity and microglia reactivity.D-GsMTx4 TFA prevented myocardial infarction in a mouse model of ischemia/reperfusion and can be used to characterize the role of excitatory MSCs in normal physiology and pathology.
  • $710
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Semaglutide
T19850910463-68-2
Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).
  • $213
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Tirzepatide Acetate(2023788-19-2 free base)
TP1111L
Tirzepatide (LY3298176) Acetate (2023788-19-2 free base) is a new molecule that can control blood glucose levels by combining dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.[3]
  • $358
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GsMTx4 TFA (1209500-46-8 free base)
TP1300
GsMTx4 TFA (1209500-46-8 free base) is a spider venom peptide that selectively inhibits cation permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families.
  • $468
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Insulin (human)
T822111061-68-0
Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin (human) has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patients.
  • $30
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Adropin (34-76) (human, mouse, rat)
T766641802086-30-1
Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance independent of obesity or food intake.
  • $127
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Tirzepatide
TP11112023788-19-2
Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity.
  • $266
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Semaglutide Acetate
T19850L1997361-85-9
Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes.
  • $239
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Bulevirtide (Myrcludex B) acetate
T35373L
Bulevirtide (Myrcludex B) acetate is a viral particle entry inhibitor that blocks the hepatocyte entry pathway for viral particles, the hepatic sodium taurine co-transport polypeptide (NTCP) receptor. It can be used in HBV and HDV infection studies.
  • $197
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Liraglutide
T6876204656-20-2
Liraglutide (Liraglutida) is a synthetic analog of glucagon-like peptide-1 (GLP-1), an agonist of the GLP-1 receptor. Liraglutide can be used to treat type 2 diabetes and chronic obesity.
  • $119
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Elamipretide
TP1095736992-21-5
Elamipretide (MTP-131) is a mitochondria-targeted antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that reduces toxic reactive oxygen species (ROS) production and stabilizes cardiolipin, with blood-brain-barrier permeability. It is a potential therapeutic agent in the rare disease of Barnes syndrome.
  • $50
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BzATP triethylammonium salt
TP2226112898-15-4
BzATP triethylammonium salt is a P2X7 receptor agonist.
  • $41
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LL-37, Human acetate(154947-66-7 free base)
TP1775L
LL-37, Human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity.
  • $118
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Avexitide
TP2100133514-43-9
Avexitide (Exendin-3 (9-39) amide) (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.
  • $198
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L-Asparaginase
TP11159015-68-3
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin.
  • $55
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740 Y-P
TQ00031236188-16-1
740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.
  • $89
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Insulin(cattle)
TP112511070-73-8
Insulin(cattle) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patients.
  • $48
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Aprotinin
T33599087-70-1
Aprotinin (Traskolan) is a broad-spectrum serine protease (BPTI) inhibitor that inhibits the activity of a number of different esterases and proteases. Aprotinin is an antifibrinolytic agent used to minimize hemorrhage during complex surgical procedures.
  • $39
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Exendin-4
T3967141758-74-9
Exendin-4 (Exenatide) is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide has a longer half-life of 2.4 hours.
  • $57
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N-Formyl-Met-Ala-Ser TFA(17351-32-5 free base)
TP1672L
N-Formyl-Met-Ala-Ser TFA (17351-32-5 free base) is a peptide that binds to formyl peptide receptors on neutrophils. This N-formylmethionine-containing peptide, called fMet-Ala-Ser, is one of the most potent and best-known peptides that interact with these receptors.
  • $50
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Retatrutide
T762792381089-83-2
Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide can be used to study obesity.
  • $247
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GLP-1(7-36), amide
T3984107444-51-9
GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.
  • $185
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Ziconotide Acetate (107452-89-1 free base)
TP1559L914454-03-8
Ziconotide Acetate (107452-89-1 free base) (Prialt) is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide Acetate (107452-89-1 free base) acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
  • $175
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Relamorelin
T34281661472-41-9In house
Relamorelin(BIM28131, RM131) is a selective and potent ghrelin growth hormone secretagogue receptor (GHSR) agonist with high affinity for GHS-1a receptor (Ki value is 0.42 ± 0.063 nM). Relamorelin(BIM28131, RM131) is also a centrally permeable pentapeptide analog that can increase growth hormone levels and accelerate gastric emptying, and has the potential to study cachexia.
  • $497
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FLAG peptide
TP127398849-88-8
FLAG peptide, an eight-amino-acid sequence (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys), includes an enterokinase-cleavage site and is utilized for the purification of recombinant proteins.
  • $30
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Pam3CSK4 TFA (112208-00-1 free base)
TP1067112208-01-2
Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1 2 agonist with EC50 of 0.47 ng mL for human TLR1 2.
  • $128
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Gastrin I, human
TP203010047-33-3
Gastrin I, human (Gastrin I (human)) is an endogenous peptide produced in the stomach that increases pepsinogen and acid secretion via the CCK2 receptor in the rat.
  • $109
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α-(difluoromethyl)-DL-Arginine
T3544969955-43-7In house
α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been shown to prevent osmotic stress-induced increases in arginine decarboxylase activity and putrescine synthesis in oat leaf cells. When combined with a variety of polyamine analogues, α-(difluoromethyl)-DL-Arginine inhibited the growth of Trypanosoma Crui in mammalian host cells at a minimum concentration of 10 mM and prevented the growth of Trypanosoma Crui in T-cell receptor alpha-deficient mouse models.
  • $64
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β-Amyloid (1-42), acetate (human)
TP1007L
β-Amyloid (1-42), acetate (human) is a peptide consisting of 42 amino acids that is part of β-Amyloid and is commonly used in Alzheimer's disease modeling.
  • $243
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MOG peptide (35-55) , mouse, rat acetate
T7657L
Myelin Oligodendrocyte Glycoprotein (MOG) peptide (35-55) , mouse, rat acetate is a MOG peptide (35-55) derivative. MOG peptide (35-55) is a part of myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide and can be used to study immune-related diseases.
  • $135
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3X FLAG peptide
TP1274402750-12-3
3X FLAG peptide consists of three repeating Asp-Tyr-Lys-Xaa-Xaa-Asp motifs with a FLAG tag at the C-terminus of the peptide.3X FLAG peptide can be used for protein identification and purification.
  • $58
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β-Amyloid (25-35)
T14284131602-53-4
β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
  • $64
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Z-IETD-FMK
T7019210344-98-2
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a cell-permeable, selective inhibitor of caspase 8.
  • $127
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Setmelanotide Acetate(920014-72-8 free base)
T12882L2759937-80-7
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
  • $133
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Cy3 NHS ester
T189461393363-07-9
Cy3 NHS ester is a fluorescent dye used to label amino groups in proteins, peptides, antibodies, and oligonucleotides. The excitation emission (Ex Em) values ​​of Cy3 NHS ester are 550 nm 570 nm.
  • $60
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Angiotensin II human acetate
T856068521-88-0
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
  • $32
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Desmopressin acetate (16679-58-6 free base)
T514462288-83-9
Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin acetate (16679-58-6 free base) works by limiting the amount of water that is eliminated in the urine. Desmopressin acetate (16679-58-6 free base) binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.
  • $45
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Cilengitide
T2494188968-51-6
Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3 5 receptor (IC50: 4.1 79 nM, in cell-free assays) with approximately 10-fold selectivity against gpIIbIIIa.
  • $45
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Cortistatin-14 acetate
TP1570L
Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 acetate shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties
  • $113
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[Tyr3]Octreotate
T67931302794-43-0
[Tyr3]Octreotate is a long peptide compound containing 8 amino acids and is a functional DOTA chelating agent with covalent bonds. [Tyr3]Octreotate binds to transmembrane receptors of SSR2-active NETs and is actively transported into cells by endocytosis, which may increase the required double-stranded DNA breaks and is a potential drug for tumor treatment.
  • $195
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Selenocysteine
T942710236-58-5
Selenocysteine ​​is considered to be the 21st amino acid in ribosome-mediated protein synthesis, and its specific incorporation is directed by the UGA codon.
  • $253
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xStAx-VHLL TFA
T36275L
xStAx-VHLL TFA is a β-catenin degrader formed by coupling xStAx to VHL ligand, has anti-cancer activity, inhibits Wnt signaling, and can be used in the study of cancer.
  • $295
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Colivelin
TP1856867021-83-8
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
  • $237
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Pepstatin
T369526305-03-3
Pepstatin (Pepsin Inhibitor S 735A) is an aspartate protease inhibitor that also inhibits HIV protease activity with specific and oral activity. Pepstatin inhibits autophagy.
  • $32
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Dihexa
T73761401708-83-5
Dihexa (Hexanoyl-Tyr-Ile-Ahx-NH2) is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) system,it binds to HGF (Kd = 65 pM),and an analog of the peptide angiotensin IV.
  • $63
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Linaclotide
T11852851199-59-2
Linaclotide, developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation, is a potent and selective guanylate cyclase C agonist.
  • $60
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LTX315 acetate
T6881L
LTX315 acetate (Oncopore acetate) is an oncolytic peptide with potent anticancer activity, with IC50 values of 34.3 µM for MRC-5, 8.3 µM for A20, and 11 µM for AT84, respectively.
  • $68
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iRGD peptide
TP12041392278-76-0
iRGD peptide (c(CRGDKGPDC)) is a 9-amino acid cyclic peptide (sequence: CRGDKGPDC) and a molecular mimicry agent that was originally identified in an in vivo screening of phage display libraries in tumor-bearing mice.
  • $72
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