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Peptides

Peptides are short chains of between two and fifty amino acids, linked by peptide bonds. Chains of less than ten or fifteen amino acids are called oligopeptides, and include dipeptides, tripeptides, and tripeptides. A polypeptide is a longer, continuous, and unbranched peptide chain of up to fifty amino acids. Hence, peptides fall under the broad chemical classes of biological oligomers and polymers, alongside nuclei acids, oligosaccharides, polysaccharides, and others. Targetmol provides more than 1000 polypeptide products, including pharmaceutical peptides, active peptides, peptide hormones, amino acid derivatives, and label peptides for scientific research only. We ensure quality by performing comprehensive analytical testing for our peptides (HPLC and LC-MS), stability testing and activity testing. Quality inspection results can be provided for customers.

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D-GsMTx4 TFA
T37697L
D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1 6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective stretch-activated channels (SACs), and attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglia reactivity. toxicity and microglia reactivity.D-GsMTx4 TFA prevented myocardial infarction in a mouse model of ischemia reperfusion and can be used to characterize the role of excitatory MSCs in normal physiology and pathology.
  • $438
4-6 weeks
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TargetMol | Inhibitor Hot
Semaglutide
T19850910463-68-2
Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).
  • $129
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GsMTx4 TFA (1209500-46-8 free base)
TP1300
GsMTx4 TFA (1209500-46-8 free base) is a spider venom peptide that selectively inhibits cation permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families.
  • $468
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Tirzepatide Acetate(2023788-19-2 free base)
TP1111L
Tirzepatide (LY3298176) Acetate (2023788-19-2 free base) is a new molecule that can control blood glucose levels by combining dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.[3]
  • $358
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TargetMol | Inhibitor Hot
Semaglutide Acetate
T19850L1997361-85-9
Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes.
  • $129
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TargetMol | Inhibitor Hot
Tirzepatide
TP11112023788-19-2
Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity.
  • $266
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TargetMol | Inhibitor Hot
Insulin (human)
T822111061-68-0
Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin (human) has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patients.
  • $30
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Adropin (34-76) (human, mouse, rat)
T766641802086-30-1
Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance independent of obesity or food intake.
  • $127
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Ceruletide
T1493217650-98-5
Ceruletide is a decapeptide that is a safe and effective cholecystokinin and cholecystokinin receptor agonist with direct spasmodic effects on the gallbladder muscle and bile duct.[1]
  • $109
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Urotensin I acetate (83930-33-0 Free base)
TP1199L
Urotensin I acetate, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively[1][2].
  • $250
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TargetMol | Inhibitor Hot
Elamipretide
TP1095736992-21-5
Elamipretide (MTP-131) is a mitochondria-targeted antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that reduces toxic reactive oxygen species (ROS) production and stabilizes cardiolipin, with blood-brain-barrier permeability. It is a potential therapeutic agent in the rare disease of Barnes syndrome.
  • $50
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TargetMol | Citations Cited
Liraglutide
T6876204656-20-2
Liraglutide (Liraglutida) is a synthetic analog of glucagon-like peptide-1 (GLP-1), an agonist of the GLP-1 receptor. Liraglutide can be used to treat type 2 diabetes and chronic obesity.
  • $119
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
LL-37, Human acetate(154947-66-7 free base)
TP1775L
LL-37, Human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity.
  • $118
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Aprotinin
T33599087-70-1
Aprotinin (Traskolan) is a broad-spectrum serine protease (BPTI) inhibitor that inhibits the activity of a number of different esterases and proteases. Aprotinin is an antifibrinolytic agent used to minimize hemorrhage during complex surgical procedures.
  • $39
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
740 Y-P
TQ00031236188-16-1
740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.
  • $89
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Avexitide
TP2100133514-43-9
Avexitide (Exendin-3 (9-39) amide) (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.
  • $135
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N-Formyl-Met-Ala-Ser TFA(17351-32-5 free base)
TP1672L
N-Formyl-Met-Ala-Ser TFA (17351-32-5 free base) is a peptide that binds to formyl peptide receptors on neutrophils. This N-formylmethionine-containing peptide, called fMet-Ala-Ser, is one of the most potent and best-known peptides that interact with these receptors.
  • $50
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TargetMol | Inhibitor Hot
BzATP triethylammonium salt
TP2226112898-15-4
BzATP triethylammonium salt is a P2X7 receptor agonist.
  • $41
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α-(difluoromethyl)-DL-Arginine
T3544969955-43-7In house
α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been shown to prevent osmotic stress-induced increases in arginine decarboxylase activity and putrescine synthesis in oat leaf cells. When combined with a variety of polyamine analogues, α-(difluoromethyl)-DL-Arginine inhibited the growth of Trypanosoma Crui in mammalian host cells at a minimum concentration of 10 mM and prevented the growth of Trypanosoma Crui in T-cell receptor alpha-deficient mouse models.
  • $64
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Somatostatin 1-28 acetate
TP2124L
Somatostatin 1-28 acetate circulates in human plasma. Approximately 46% of the total somatostatin-like immunoreactivity in plasma is due to Somatostatin 1-28 acetate.
  • $508
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L-Asparaginase
TP11159015-68-3
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin.
  • $55
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TargetMol | Inhibitor Hot
MOG peptide (35-55) , mouse, rat acetate
T7657L
Myelin Oligodendrocyte Glycoprotein (MOG) peptide (35-55) , mouse, rat acetate is a MOG peptide (35-55) derivative. MOG peptide (35-55) is a part of myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide and can be used to study immune-related diseases.
  • $135
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Pam3CSK4 TFA (112208-00-1 free base)
TP1067112208-01-2
Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1 2 agonist with EC50 of 0.47 ng mL for human TLR1 2.
  • $128
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Insulin(cattle)
TP112511070-73-8
Insulin(cattle) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patients.
  • $48
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Ziconotide Acetate (107452-89-1 free base)
TP1559L914454-03-8
Ziconotide Acetate (107452-89-1 free base) (Prialt) is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide Acetate (107452-89-1 free base) acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
  • $175
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TargetMol | Citations Cited
GLP-1(7-36), amide
T3984107444-51-9
GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.
  • $185
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TargetMol | Citations Cited
Retatrutide
T762792381089-83-2
Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide can be used to study obesity.
  • $247
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FLAG peptide
TP127398849-88-8
FLAG peptide, an eight-amino-acid sequence (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys), includes an enterokinase-cleavage site and is utilized for the purification of recombinant proteins.
  • $30
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TargetMol | Citations Cited
Relamorelin
T34281661472-41-9In house
Relamorelin(BIM28131, RM131) is a selective and potent ghrelin growth hormone secretagogue receptor (GHSR) agonist with high affinity for GHS-1a receptor (Ki value is 0.42 ± 0.063 nM). Relamorelin(BIM28131, RM131) is also a centrally permeable pentapeptide analog that can increase growth hormone levels and accelerate gastric emptying, and has the potential to study cachexia.
  • $497
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Setmelanotide Acetate(920014-72-8 free base)
T12882L2759937-80-7
Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).
  • $133
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Exendin-4
T3967141758-74-9
Exendin-4 (Exenatide) is a glucagon-like peptide-1 receptor (GLP-1) agonist (IC50: 3.22 nM). Exenatide is a 39 amino acid peptide. Compared to GLP-1, exenatide has a longer half-life of 2.4 hours.
  • $57
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
GIP (1-39) acetate
TP2017L
GIP (1-39) acetate is a gastric inhibitory peptide (GIP) purified from porcine intestine and stimulates insulin secretion.
  • $580
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Gastrin I, human
TP203010047-33-3
Gastrin I, human (Gastrin I (human)) is an endogenous peptide produced in the stomach that increases pepsinogen and acid secretion via the CCK2 receptor in the rat.
  • $109
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β-Amyloid (25-35)
T14284131602-53-4
β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
  • $64
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β-Amyloid (1-42), acetate (human)
TP1007L
β-Amyloid (1-42), acetate (human) is a peptide consisting of 42 amino acids that is part of β-Amyloid and is commonly used in Alzheimer's disease modeling.
  • $243
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(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
T9691L
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membrane.
  • $67
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3X FLAG peptide
TP1274402750-12-3
3X FLAG peptide consists of three repeating Asp-Tyr-Lys-Xaa-Xaa-Asp motifs with a FLAG tag at the C-terminus of the peptide.3X FLAG peptide can be used for protein identification and purification.
  • $58
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Difelikefalin acetate
TP25012803411-76-7
Difelikefalin acetate (CR 845 acetate) is a peripherally restricted kappa opioid receptor agonist. CR845 exhibit low P450 CYP inhibition and low penetration into the brain.
  • $100
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Boc-Asp(OMe)-fluoromethyl ketone
T39308187389-53-3In house
Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
  • $40
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Desmopressin acetate (16679-58-6 free base)
T514462288-83-9
Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin acetate (16679-58-6 free base) works by limiting the amount of water that is eliminated in the urine. Desmopressin acetate (16679-58-6 free base) binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.
  • $45
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TargetMol | Citations Cited
PKC β pseudosubstrate acetate
TP1955L
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.
  • $175
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DOTATATE acetate
T39193177943-89-4
DOTATATE acetate is a DOTA-binding peptide, a growth inhibitor analog, and a novel PET tracer involved in the assessment of functional imaging of highly differentiated neuroendocrine tumors (NETs).
  • $64
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Angiotensin II human acetate
T856068521-88-0
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
  • $32
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TargetMol | Citations Cited
Urocortin (rat) acetate
TP1020L
Urocortin (rat) acetate is an agonist of endogenous CRFR with Kis of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively. Urocortin (rat) acetate is a neuropeptide.
  • $159
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Dermaseptin acetate
TP1839L
Dermaseptin acetate, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration[1].
  • $217
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Z-IETD-FMK
T7019210344-98-2
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a cell-permeable, selective inhibitor of caspase 8.
  • $127
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TargetMol | Inhibitor Sale
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xStAx-VHLL TFA
T36275L
xStAx-VHLL TFA is a β-catenin degrader formed by coupling xStAx to VHL ligand, has anti-cancer activity, inhibits Wnt signaling, and can be used in the study of cancer.
  • $295
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Linaclotide
T11852851199-59-2
Linaclotide, developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation, is a potent and selective guanylate cyclase C agonist.
  • $60
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