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Pack Size | Price | Availability | Quantity |
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5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Selcopintide acetate (Cpne7-DP), a synthetic peptide, mirrors the 344-353 amino acid sequence of the hCPNE7 protein. It effectively mimics CPNE7's in vitro activity, enhancing the expression of odontoblast markers like DSPP and Nestin. Selcopintide acetate has been shown to facilitate dentin regeneration across varying levels of dentinal defects, with the regenerated tissue exhibiting true dentin properties [1]. |
In vitro | Selcopintide (Cpne7-DP) acetate directly penetrates into odontoblastic (MDPC-23) cells [1]. Additionally, Selcopintide acetate at dosages of 1 and 10 μg enhances the activity of the dspp promoter in a dose-dependent manner [1]. |
In vivo | Selcopintide (Cpne7-DP; 10 µg in 0.5% fibrin gel mixed with human DPC cells before subcutaneous transplantation) acetate promotes dentin-like tissue formation and the regeneration of tubular dentin and dentinal tubule occlusion in both shallow and deep cavity models [1]. |
Alias | Cpne7-DP acetate |
Molecular Weight | 1444.68 |
Formula | C64H109N21O17 |
Cas No. |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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