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Selcopintide acetate

Name: Selcopintide acetate
Brand: TargetMol
SKU: T78024
Rating: 4.5 (1 reviews)

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Catalog No. T78024

Alias Cpne7-DP acetate

Selcopintide acetate (Cpne7-DP), a synthetic peptide, mirrors the 344-353 amino acid sequence of the hCPNE7 protein. It effectively mimics CPNE7's in vitro activity, enhancing the expression of odontoblast markers like DSPP and Nestin. Selcopintide acetate has been shown to facilitate dentin regeneration across varying levels of dentinal defects, with the regenerated tissue exhibiting true dentin properties [1].

Selcopintide acetate

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Catalog No. T78024Alias Cpne7-DP acetate

Pack Size	Price	Availability	Quantity
5 mg	Inquiry	Backorder
50 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description	Selcopintide acetate (Cpne7-DP), a synthetic peptide, mirrors the 344-353 amino acid sequence of the hCPNE7 protein. It effectively mimics CPNE7's in vitro activity, enhancing the expression of odontoblast markers like DSPP and Nestin. Selcopintide acetate has been shown to facilitate dentin regeneration across varying levels of dentinal defects, with the regenerated tissue exhibiting true dentin properties [1].
In vitro	Selcopintide (Cpne7-DP) acetate directly penetrates into odontoblastic (MDPC-23) cells [1]. Additionally, Selcopintide acetate at dosages of 1 and 10 μg enhances the activity of the dspp promoter in a dose-dependent manner [1].
In vivo	Selcopintide (Cpne7-DP; 10 µg in 0.5% fibrin gel mixed with human DPC cells before subcutaneous transplantation) acetate facilitates dentin-like tissue formation and regenerates tubular dentin, including dentinal tubule occlusion, in both shallow and deep cavity models [1].
Alias	Cpne7-DP acetate

Chemical Properties

Molecular Weight	1444.68
Formula	C₆₄H₁₀₉N₂₁O₁₇

Storage & Solubility Information

Storage

keep away from moisture | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Selcopintide AcetateCpne7-DP Acetate