iRGD peptide 1 TFA

Name: iRGD peptide 1 TFA
Brand: TargetMol
SKU: T77996
Price: 29 USD
Availability: InStock
Rating: 4.5 (1 reviews)

iRGD Peptide 1 TFA is a prototypic tumor-homing peptide with tissue-penetrating capabilities, facilitating deep delivery of therapeutic agents into extravascular tumor tissue. Additionally, it possesses anti-metastatic activity [1].

Catalog No. T77996

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iRGD peptide 1 TFA

Catalog No. T77996

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Product Introduction

Bioactivity

Description	iRGD Peptide 1 TFA is a prototypic tumor-homing peptide with tissue-penetrating capabilities, facilitating deep delivery of therapeutic agents into extravascular tumor tissue. Additionally, it possesses anti-metastatic activity [1].
In vitro	The iRGD peptide 1 (iRGD) attenuates tumor cell migration and elicits chemorepulsion in vitro, contingent upon CendR and NRP-1 pathways. This peptide precipitates marked retraction of cell extensions and partial cell detachment, contributing to its repellent effect. Such responses are notably accentuated upon fibronectin exposure, implying CendR's instrumental role in modulating integrin activity [1].
In vivo	The iRGD peptide 1 (CRGDKGPDC; 4 μmol/kg; intravenous; qod; 21 days) effectively suppresses spontaneous metastasis in mice [1].

Chemical Properties

Molecular Weight	1064.08
Formula	C₃₇H₆₀F₃N₁₃O₁₆S₂

Storage & Solubility Information

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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