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iRGD peptide 1 TFA

Name: iRGD peptide 1 TFA
Brand: TargetMol
SKU: T77996
Price: 497 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T77996

iRGD Peptide 1 TFA is a prototypic tumor-homing peptide with tissue-penetrating capabilities, facilitating deep delivery of therapeutic agents into extravascular tumor tissue. Additionally, it possesses anti-metastatic activity [1].

iRGD peptide 1 TFA

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Catalog No. T77996

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50 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description	iRGD Peptide 1 TFA is a prototypic tumor-homing peptide with tissue-penetrating capabilities, facilitating deep delivery of therapeutic agents into extravascular tumor tissue. Additionally, it possesses anti-metastatic activity [1].
In vitro	The iRGD peptide 1 (iRGD) attenuates tumor cell migration and elicits chemorepulsion in vitro, contingent upon CendR and NRP-1 pathways. This peptide precipitates marked retraction of cell extensions and partial cell detachment, contributing to its repellent effect. Such responses are notably accentuated upon fibronectin exposure, implying CendR's instrumental role in modulating integrin activity [1].
In vivo	The iRGD peptide 1 (CRGDKGPDC; 4 μmol/kg; intravenous; qod; 21 days) effectively suppresses spontaneous metastasis in mice [1].

Chemical Properties

Molecular Weight	1064.08
Formula	C₃₇H₆₀F₃N₁₃O₁₆S₂

Storage & Solubility Information

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keep away from moisture | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc