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PD 156252

Catalog No. TP2613Cas No. 175592-65-1

PD 156252 is a hexapeptide and a highly potent endothelin (ET) antagonist, exhibiting enhanced binding affinity for rabbit ETA and rat ETB receptor subtypes with IC50 values of 1.0 nM and 40 nM, respectively.

PD 156252

PD 156252

Catalog No. TP2613Cas No. 175592-65-1
PD 156252 is a hexapeptide and a highly potent endothelin (ET) antagonist, exhibiting enhanced binding affinity for rabbit ETA and rat ETB receptor subtypes with IC50 values of 1.0 nM and 40 nM, respectively.
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Product Introduction

Bioactivity
Description
PD 156252 is a hexapeptide and a highly potent endothelin (ET) antagonist, exhibiting enhanced binding affinity for rabbit ETA and rat ETB receptor subtypes with IC50 values of 1.0 nM and 40 nM, respectively.
Chemical Properties
Molecular Weight964.16
FormulaC53H69N7O10
Cas No.175592-65-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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