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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $537 | Backorder | |
10 mg | $872 | Backorder | |
50 mg | Inquiry | Backorder | |
100 mg | Inquiry | Backorder |
Description | Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively hinders the processing of over-expressed gp160 and suppresses HIV-1 replication. |
In vitro | Decanoyl-RVKR-CMK (DecRVKRcmk) TFA effectively inhibits HIV-2 ROD replication by impeding the processing of envelope glycoprotein precursors in Jurkat lymphocyte cells[1]. Additionally, it obstructs the regulated secretion of VGF[2]. In a cell viability assay involving HeLaCD4 cells infected with recombinant vaccinia viruses at a multiplicity of infection (MOI) of 5 PFU/mL, concentrations of 35 and 70 μM were tested over a period of 7 days. The results demonstrated that a peptide concentration of 35 μM markedly reduced ex vivo HIV-1 and HIV-2 replication rates by 70-80%. |
Alias | DecRVKRcmk TFA, Decanoyl-RVKR-CMK TFA |
Molecular Weight | 858.45 |
Formula | C36H67ClF3N11O7 |
Cas No. | 2098497-25-5 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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