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Bax inhibitor peptide V5 acetate

Bax inhibitor peptide V5 acetate
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
Catalog No. T10463L
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Purity:99.2%
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Bax inhibitor peptide V5 acetate

Catalog No. T10463LAlias Bax inhibitor peptide V5 acetate(579492-81-2 free base)

Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$44In Stock
2 mg$61In Stock
5 mg$90In Stock
10 mg$132In Stock
25 mg$290In Stock
50 mg$478In Stock
100 mg$619In Stock
200 mg$809In Stock
1 mL x 10 mM (in DMSO)$143In Stock
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Product Introduction

Bioactivity
Description
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
In vitro
Bax inhibitor peptide V5 (BIP-V5; 0-50 μM) decreases cell death in STF-cMyc cells but not in SW620 or NCI-H23 cells.[1]. V5 treatment upregulates expression of anti-apoptotic proteins Bcl-2 and XIAP by more than 3- and 11-fold and downregulates expression of apoptosis-inducing proteins Bax, Bad, and nuclear factor-κB-p65 by 10, 30, and nearly 50%, respectively[2].
In vivo
Bax inhibitor peptide V5 (BIP-V5; 100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation in mice model[2].
AliasBax inhibitor peptide V5 acetate(579492-81-2 free base)
Chemical Properties
Molecular Weight646.85
FormulaC29H54N6O8S
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 100 mg/mL (170.42 mM), Sonication is recommended.
DMSO: 100 mg/mL (170.42 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.5460 mL7.7298 mL15.4595 mL77.2977 mL
5 mM0.3092 mL1.5460 mL3.0919 mL15.4595 mL
10 mM0.1546 mL0.7730 mL1.5460 mL7.7298 mL
20 mM0.0773 mL0.3865 mL0.7730 mL3.8649 mL
50 mM0.0309 mL0.1546 mL0.3092 mL1.5460 mL
100 mM0.0155 mL0.0773 mL0.1546 mL0.7730 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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