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Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Urocortin, rat TFA is a neuropeptide and a potent endogenous CRFR agonist (Kis: 0.97 nM, 1.5 nM, and 13 nM for mouse CRF2β, rat CRF2α, and human CRF1). |
Targets&IC50 | CRF2α (rat):1.5 nM (ki), CRF2β (mouse):0.97 nM (ki), CRF1 (human):ki: 13 nM |
In vitro | In stably transfected Chinese hamster ovary cells, Urocortin, rat induces cAMP generation with EC50 of 0.15 nM, 0.063 nM, and 0.087 nM for human CRF1, rat CRF2α, and mouse CRF2β, respectively [2]. |
In vivo | Urocortin, rat (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such an effect also observed in mice after 1 μg of Urocortin, rat (i.c.v.). It has the potential of inducing anxiogenic behavior [3]. |
Alias | Urocortin (Rattus norvegicus) (TFA), Rat urocortin TFA, Urocortin, rat TFA |
Molecular Weight | 4821.28 |
Formula | C208H339N62F3O66 |
Cas No. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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