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CTP-NBD
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Catalog No. T82665Cas No. 1268513-27-4
CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in studies of colitis [1] [2].
CTP-NBD
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Catalog No. T82665Cas No. 1268513-27-4
CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in studies of colitis [1] [2].
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| 5 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in studies of colitis [1] [2]. |
| In vitro | CTP-NBD (200 μM, 6h) inhibits TNF-α-induced luciferase activity in HCT116 cells [1]. |
| In vivo | CTP-NBD was ineffective in reducing inflammation in a colitis rat model; however, the modified, colon-targeted CTP-NBD showed oral activity and was capable of decreasing inflammation in the same model [2]. |
| Molecular Weight | 2805.12 |
| Formula | C121H194N46O32 |
| Cas No. | 1268513-27-4 |
Storage & Solubility Information
| Storage | keep away from moisture | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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