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Diethylmaleate
Catalog No. T21480Cas No. 141-05-9
Alias Maleic acid, diethyl ester, DIETHYL MALEATE
Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.
Diethylmaleate
Catalog No. T21480Alias Maleic acid, diethyl ester, DIETHYL MALEATECas No. 141-05-9
Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $41 | In Stock | |
| 200 mg | $68 | In Stock | |
| 500 mg | $124 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $45 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB. |
| In vitro | Diethylmaleate and iodoacetate in combination caused augmented damage to astrocytes in a time- and concentration-dependent manner[1]. |
| In vivo | In TR- rats, in spite of a dilatation of the Golgi apparatus and of the endoplasmic reticulum. It is unlikely that the alterations in the Golgi apparatus (and the endoplasmic reticulum) induced by diethylmaleate play a role in the canalicular secretion of diethylmaleate. |
| Alias | Maleic acid, diethyl ester, DIETHYL MALEATE |
| Molecular Weight | 172.18 |
| Formula | C8H12O4 |
| Cas No. | 141-05-9 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/ml (348.47 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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