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TargetMol | Compound Library

Hematonosis Compound Library

Catalog No. L8400

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases. Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L8400

Hematonosis Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2405 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
  • Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Apoptosis
NF-κB
Autophagy
PI3K
EGFR
HDAC
mTOR
Wnt/beta-catenin
JAK
Akt
STAT
FLT
GSK-3
AMPK
Antibacterial
Bcl-2 Family
VEGFR
Endogenous Metabolite
CDK
Proteasome
c-Kit
Bcr-Abl
PDGFR
HIF/HIF Prolyl-Hydroxylase
Histone Methyltransferase
Src
HER
HIF
ERK
Dehydrogenase
COX
Tyrosine Kinases
Hedgehog/Smoothened
DNA/RNA Synthesis
HIV Protease
DNA-PK
Antibiotic
FGFR
Parasite
Reactive Oxygen Species
S6 Kinase
p38 MAPK
Caspase
Epigenetic Reader Domain
TNF
ATM/ATR
Topoisomerase
PARP
PKC
DNA Methyltransferase
PDK
JNK
Pim
IL Receptor
Potassium Channel
Gamma-secretase
Aurora Kinase
Influenza Virus
Ferroptosis
c-Met/HGFR
Mitophagy
PPAR
Microtubule Associated
PD-1/PD-L1
BTK
c-RET
c-Myc
ALK
Antifungal
Virus Protease
Raf
CXCR
Cytochromes P450
MAPK
PI4K
MEK
TAM Receptor
E1/E2/E3 Enzyme
DPP-4
IGF-1R
PKA
Calcium Channel
Nrf2
AChR
p53
Histone Demethylase
Nucleoside Antimetabolite/Analog
Smo
c-Fms
NO Synthase
HCV Protease
Antioxidant
Phosphatase
Chk
Trk receptor
Casein Kinase
Syk
Isocitrate Dehydrogenase (IDH)
Antiviral
IκB/IKK
Beta Amyloid
MMP
Lipoxygenase
Interleukin
TLR
PLK
NOS
ROS
P-gp
Sodium Channel
FAK
CSF-1R
PDE
Drug Metabolite
PTEN
HSP
DYRK
SIK
Mitochondrial Metabolism
Antifection
Histone Acetyltransferase
GABA Receptor
5-HT Receptor
Mdm2
Adenosine Receptor
Rho
Cysteine Protease
ROCK
DUB
TGF-beta/Smad
Prostaglandin Receptor
SARS-CoV
Sirtuin
MELK
Retinoid Receptor
Anti-infection
IRAK
Tyrosinase
Integrin
Estrogen/progestogen Receptor
Adrenergic Receptor
IAP
Immunology/Inflammation related
DNA Alkylation
HSV
GluR
CaMK
Aminopeptidase
transporter
Cannabinoid Receptor
ROS Kinase
ATPase
Chloride channel
Carbonic Anhydrase
DNA Alkylator/Crosslinker
Histamine Receptor
HBV
TRP/TRPV Channel
Glucosidase
Cholinesterase (ChE)
MNK
Porcupine
Ras
S1P Receptor
ADC Cytotoxin
Transferase
DHFR
Dopamine Receptor
LTR
IFNAR
BACE
RAAS
Tie-2
GTPase
Estrogen Receptor/ERR
Hck
Serine/threonin kinase
Liver X Receptor
MAO
IRE1
UGT
LDL
NMDAR
ACK1
Lipid
BCRP
PGE Synthase
Acyltransferase
Ephrin Receptor
Methionine Adenosyltransferase (MAT)
Reverse Transcriptase
Adenosine Deaminase
SGK
NOD
Thrombin
NOD-like Receptor (NLR)
Kinesin
NEDD8
CRM1
Amino Acids and Derivatives
NADPH
TOPK
Cholecystokinin Receptor
Serine Protease
Antifolate
Leukotriene Receptor
PYK2
NAMPT
Aryl Hydrocarbon Receptor
RIP kinase
GRK
Monoamine Transporter
Opioid Receptor
Fatty Acid Synthase
PAK
CCR
KSP
cAMP
Androgen Receptor
SGLT
ATP Citrate Lyase
Beta-Secretase
Survivin
Hippo pathway
GPR
CRISPR/Cas9
Phospholipase
Discoidin Domain Receptor (DDR)
MLK
Melanin-concentrating Hormone Receptor (MCHR)
Proton pump
PROTACs
Adenylyl Cyclase
MicroRNA
Monocarboxylate transporter
NPC1L1
RAR/RXR
MALT
ROR
NUDIX hydrolase
MyD88
YAP
Arginase
LPL Receptor
Reductase
Na+/Ca2+ Exchanger
Lipase
PERK
gp120/CD4
Glutathione Peroxidase
Factor Xa
Progesterone Receptor
OCT
MRP
Glucokinase
Glutaminase
Glucocorticoid Receptor
Myosin
Haspin Kinase
DNA gyrase
ABC Transporter
Guanylate cyclase
PAD
Thrombopoietin Receptor
DNA
Telomerase
Wee1
OXPHOS
STING
Free radical scavengers
Decarboxylase
hCE
RSV
Neprilysin
GST
Protease
Aromatase
KLF
Cuproptosis
DAPK
Platelet aggregation
BMI-1
NADPH-oxidase
Sigma receptor
Protease-activated Receptor
p97
AhR
CFTR
Imidazoline Receptor
PKM
Monoamine Oxidase