Hematonosis Compound Library

Catalog No. L8400

Library Compound List Excel SDF

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In addition to hematological malignancies, such as leukemia and lymphomas, children and adolescents can suffer blood disorder, that are not classified as cancer, but may lead to severe diseases and therefore require treatment. These blood disorders include severe aplastic anemia (SAA), thalassemia, immune (idiopathic) thrombocytopenic purpura, congenital neutropenia, hemophilia, sickle-cell disease, iron deficiency anemia and various other diseases. In the past, due to the lack of effective treatments, many diseases have been called "incurable diseases". In recent years, with in-depth development of medical research, the treatment of blood diseases has been significantly improved. Modern medicine uses hormones, chemotherapy and other methods for the treatment of blood diseases, but the side effects are large, and the patient has a low cure rate and is prone to recurrence. Bone marrow transplantation for the treatment of leukemia was introduced then the cure rate of leukemia was improved. However, the bone marrow resources were very scarce, and a large part of the donated bone marrow was inconsistent with the patient's HLA, even if the transplant was successful, and the recurrence rate was as high as 70% within 5 years. Therefore, it is necessary to develop new therapies and drugs for the treatment of hematologic diseases.

Hematonosis Compound Library from TargetMol provides you with compounds related to hematologic diseases that can be used for high throughput and high content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

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Product Description

A unique collection of 524 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);
Effective tool for research in functions of the hematologic system and related diseases, such as hemophilia, leukemia, β-thalassemia;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
NMR and HPLC/LCMS validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..

10. Blood. 2021, 137(11): 1478-1490. 11. Nucleic Acids Research. 2021. 12. Nature Communications. 2023, 14(1): 7574. 13. Advanced Science. 2020, 7(16): 2000925. 14. Angewandte Chemie. 2021. 15. Acta Pharmaceutica Sinica B. 2022. 16. Protein & Cell. 2021, 12(11): 877-888. 17. Bone Research. 2023, 11(1): 54. 18. Pharmacology & Therapeutics. (2021): 107930. 19. Nature Communications. 2021, 12(1): 1-12. 20. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Apoptosis (156)

Autophagy (103)

PI3K (33)

DNA/RNA Synthesis (31)

Bcr-Abl (25)

Endogenous Metabolite (25)

FLT (24)

HDAC (24)

CDK (23)

Topoisomerase (21)

Histone Methyltransferase (18)

c-Kit (17)

Antibacterial (17)

ALK (16)

Dehydrogenase (16)

Src (16)

PDGFR (15)

mTOR (14)

JAK (14)

Nucleoside Antimetabolite/Analog (13)

VEGFR (12)

HIV Protease (11)

FGFR (10)

BCL (10)

TAM Receptor (10)

Antibiotic (10)

Epigenetic Reader Domain (10)

Microtubule Associated (9)

E1/E2/E3 Enzyme (9)

Proteasome (9)

PKC (9)

PLK (8)

Aurora Kinase (8)

AMPK (8)

Tyrosine Kinases (8)

Mitophagy (8)

Influenza Virus (8)

DNA Alkylator/Crosslinker (8)

c-Met/HGFR (8)

NF-κB (7)

BTK (7)

GSK-3 (7)

c-RET (7)

Trk receptor (7)

Reactive Oxygen Species (6)

STAT (6)

Antifolate (6)

Ligand for E3 Ligase (6)

COX (6)

HSP (6)

Caspase (5)

Akt (5)

c-Fms (5)

ROS (5)

TNF (5)

Retinoid Receptor (5)

Isocitrate Dehydrogenase (IDH) (5)

Antifungal (5)

Syk (5)

DNA Alkylation (4)

Histone Demethylase (4)

Ferroptosis (4)

ROS Kinase (4)

Virus Protease (4)

ERK (4)

Chk (4)

AChR (4)

MEK (4)

Raf (4)

IGF-1R (4)

DNA-PK (4)

Mdm2 (4)

Parasite (4)

Ras (4)

p53 (3)

Nrf2 (3)

IRAK (3)

Potassium Channel (3)

Rho (3)

Gamma-secretase (3)

Aminopeptidase (3)

CSF-1R (3)

Pim (3)

Transferase (3)

Ligands for Target Protein for PROTAC (3)

HIF/HIF Prolyl-Hydroxylase (3)

Smo (3)

IL Receptor (3)

Wnt/beta-catenin (3)

PROTACs (3)

Molecular Glues (3)

HBV (3)

Hedgehog/Smoothened (3)

Sirtuin (3)

DUB (3)

S6 Kinase (3)

DNA Methyltransferase (3)

IAP (3)

Adenosine Receptor (3)

Mitochondrial Metabolism (3)

P-gp (3)

ATM/ATR (3)

TOPK (2)

Thrombin (2)

Androgen Receptor (2)

transporter (2)

EGFR (2)

FAK (2)

BMI-1 (2)

Adenosine deaminase (2)

NAMPT (2)

MAPK (2)

Kinesin (2)

Sodium Channel (2)

HSV (2)

CaMK (2)

Phospholipase (2)

GABA Receptor (2)

Antiviral (2)

Interleukin (2)

Casein Kinase (2)

Liver X Receptor (2)

MMP (2)

KSP (2)

p38 MAPK (2)

IκB/IKK (2)

Phosphatase (2)

NEDD8 (2)

PKA (2)

SARS-CoV (2)

Histone Acetyltransferase (2)

IRE1 (2)

TGF-beta/Smad (1)

Methionine Adenosyltransferase (MAT) (1)

MNK (1)

GTPase (1)

PAK (1)

NO Synthase (1)

MLK (1)

JNK (1)

DNA (1)

ATPase (1)

ACK (1)

Hck (1)

Adrenergic Receptor (1)

Immunology/Inflammation related (1)

OXPHOS (1)

Serine/threonin kinase (1)

PD-1/PD-L1 (1)

HCV Protease (1)

Integrin (1)

Dopamine Receptor (1)

Histamine Receptor (1)

Glutaminase (1)

PPAR (1)

p97 (1)

Fatty Acid Synthase (1)

Chloride channel (1)

LTR (1)

Lipid (1)

Ephrin Receptor (1)

KLF (1)

NADPH (1)

Amino Acids and Derivatives (1)

DHFR (1)

c-Myc (1)

Survivin (1)

MELK (1)

Cysteine Protease (1)

Hippo pathway (1)

MRP (1)

DPP-4 (1)

Haspin Kinase (1)

CXCR (1)

HIF (1)

BCRP (1)

Reverse Transcriptase (1)

CRM1 (1)

GluR (1)

Estrogen/progestogen Receptor (1)

TLR (1)

DNA gyrase (1)

NMDAR (1)

P450 (1)

Anti-infection (1)

Monocarboxylate transporter (1)

GPR (1)

MALT (1)

Antifection (1)

SGLT (1)

Tie-2 (1)

Lipoxygenase (1)

DYRK (1)

S1P Receptor (1)

VDAC (1)

Wee1 (1)

Aromatase (1)

Serine Protease (1)

Monoamine Transporter (1)

Drug Metabolite (1)

YAP (1)

PAD (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty