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Sodium salicylate

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Catalog No. T0335Cas No. 54-21-7
Alias Salicylic acid sodium salt, 2-Hydroxybenzoic acid sodium salt

Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.

Sodium salicylate

Sodium salicylate

🥰Excellent
Purity: 100%
Catalog No. T0335Alias Salicylic acid sodium salt, 2-Hydroxybenzoic acid sodium saltCas No. 54-21-7
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
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500 mg$45In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.
In vitro
Sodium salicylate acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. Sodium salicylate inhibits the activation of NF-kappa B, and also inhibits NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells. [1] Sodium salicylate also induces apoptosis via p38 MAPK and inhibits TNF-induced JNK/stress-activated protein kinase activation. [2]
AliasSalicylic acid sodium salt, 2-Hydroxybenzoic acid sodium salt
Chemical Properties
Molecular Weight160.11
FormulaC7H5NaO3
Cas No.54-21-7
Smiles[Na+].Oc1ccccc1C(=O)[O-]
Relative Density.0.56 g/cm3. Temperature:25 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (312.29 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: 29 mg/mL (181.1 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM6.2457 mL31.2285 mL62.4571 mL312.2853 mL
5 mM1.2491 mL6.2457 mL12.4914 mL62.4571 mL
10 mM0.6246 mL3.1229 mL6.2457 mL31.2285 mL
20 mM0.3123 mL1.5614 mL3.1229 mL15.6143 mL
50 mM0.1249 mL0.6246 mL1.2491 mL6.2457 mL
100 mM0.0625 mL0.3123 mL0.6246 mL3.1229 mL

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