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TargetMol | Compound Library

FDA-Approved Kinase Inhibitor Library

Catalog No. L1610

Kinases are a class of enzymes that facilitates phosphorylation, by transferring phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules. A common group of kinases are the protein kinases, which act on specific proteins to phosphorylate them and alter their activity. Protein kinases are involved in a range of cell signaling and regulatory processes and play an important role in cell growth, metabolism, differentiation and apoptosis. Protein kinases have been associated with many diseases, including cancer, inflammatory diseases, cardiovascular diseases and neurological disorders. Therefore, targeting protein kinases has emerged as a promising therapeutic strategy for the treatment of related diseases. Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs that target kinases. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、RAF、EGFR、MEK、SAPK、GSK、MLCK、Src-family、IKK、PDGFR、VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1610

FDA-Approved Kinase Inhibitor Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
  • All compounds have undergone preclinical studies and clinical trials, approved for marketing by FDA, EMA, PMDA, etc., with proven biological activity and safety.
  • Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc.
  • NMR, HPLC/LCMS and other assay techniques to ensure the correct structure and high purity of the product and reduce false positives.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Autophagy
Apoptosis
EGFR
VEGFR
c-Kit
PDGFR
JAK
FGFR
FLT
Src
Bcr-Abl
c-Met/HGFR
Tyrosine Kinases
PKC
CDK
Raf
ALK
Mitophagy
Antibacterial
NF-κB
PI3K
Endogenous Metabolite
AMPK
c-RET
Adrenergic Receptor
BTK
CaMK
mTOR
Sodium Channel
Antibiotic
Ferroptosis
PKA
Trk receptor
5-HT Receptor
MEK
TAM Receptor
Calcium Channel
ERK
ROCK
Potassium Channel
HER
HIV Protease
Histamine Receptor
Parasite
PDE
ROS
COX
Akt
AChR
Ras
ROS Kinase
Dopamine Receptor
p38 MAPK
Antifungal
GSK-3
Serine/threonin kinase
Influenza Virus
IκB/IKK
Topoisomerase
Glucosidase
PAK
IGF-1R
SARS-CoV
c-Fms
P450
Syk
FAK
ROR
Ligands for Target Protein for PROTAC
LPL Receptor
Adenosine Receptor
NADPH
Glutathione Peroxidase
TOPK
Phosphatase
Serine Protease
Serotonin Transporter
IRE1
Hexokinase
Aurora Kinase
Lipoxygenase
Interleukin
DNA/RNA Synthesis
MAPK
P-gp
Ephrin Receptor
Nrf2
TNF
Microtubule Associated
Tyrosinase
S1P Receptor
PKM
Chloride channel
Proton pump
Transferase
DHFR
DNA-PK
HCV Protease
Integrin
Estrogen/progestogen Receptor
Dehydrogenase
YAP
Antioxidant
IFNAR
JNK
gp120/CD4
Virus Protease
Melatonin Receptor
HBV
PPAR
Hck
Antifolate
Nucleoside Antimetabolite/Analog
Caspase
TRP/TRPV Channel
CSF-1R
LDL
GRK
Phosphorylase
Mitochondrial Metabolism
Monoamine Transporter
Reactive Oxygen Species
HSV
IL Receptor
Chk
PAD
ACK
GluR
Norepinephrine
DNA
Indoleamine 2,3-Dioxygenase (IDO)
TGF-beta/Smad
ATP Citrate Lyase
AChE
Antiviral
Sirtuin
Beta Amyloid
HDAC
Hydroxylase
PLK
Gap Junction Protein
Anti-infection
NADPH-oxidase
S6 Kinase
Sigma receptor
HIF/HIF Prolyl-Hydroxylase
NO Synthase

Keywords