Drug Repurposing Compound Library

Catalog No. L9200

Library Compound List Excel SDF

Traditional de novo drug discovery and development involves an HTS campaign for de novo candidate hits and requires highly specialized screening facilities and compound libraries containing several million compounds. It is a time consuming and expensive process. As the regulation for drug safety and efficacy is increasingly getting complex, the cost of developing new drugs is keeping skyrocket. Drug repositioning, also known as old drugs for new uses, is an effective strategy to find new indications for existing drugs and has recently drawn attention and has led to several blockbuster drugs because of its high efficiency and low-cost. High-content screens, new biomarkers, noninvasive imaging techniques, and advanced in bioinformatics have created new opportunities for pursuing novel indications for approved compounds.

The Drug Repurposing Compound Library by TargetMol, containing 4630 approved and clinical drugs, which have undergone extensive preclinical studies and have well-characterized bioactivities, safety and bioavailability – properties which could dramatically accelerate drug development and optimization, is a good tool for drug repurposing and cell induction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

Request for Quote

If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

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Product Description

A unique collection of 4630 approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS);
An effective tool for discovering new with old drugs, cell induction, and new drug target screening;
All approved drugs collected in this library are approved by Food and Drug Administration (FDA), the European Medicine Agency (EMA), or National Medical Products Administration (NMPA), or included in the US Pharmacopeia (USP) Dictionary, the British Pharmacopoeia (BP), the European Pharmacopoeia (EP), the Japanese Pharmacopoeia (JP), or Chinese Pharmacopoeia (CP) Dictionary;
Covers various research areas, such as cancer, cardiovascular disease, immunology, respiratory system, etc.
Covers various targets, such as 5-HT Receptor, Sodium Channel, p38 MAPK, PI3K, MEK, etc.
Detailed compound information with structure, target, activity, and brief introduction;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Journal of Medicinal Chemistry. 2023. 2. Cell Stem Cell. 2022 Apr 29(4) 545–558. 3. Science Bulletin. 2022. 4. Science Translational Medicine. 2022, 14(656): eabn3231. 5. Science Advances. 2023, 9(9): eade3760. 6. Nature. 2020, 582: 289-293. 7. Nature Biotechnology. 2021, 39(11): 1444-1452. 8. Nature Communications. 2022, 13(1): 1-15.. 9. Nature Communications. 2023, 14(1): 1020..

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Library Composition

Autophagy (460)

Antibacterial (441)

Apoptosis (434)

Antibiotic (395)

Endogenous Metabolite (327)

5-HT Receptor (210)

Adrenergic Receptor (174)

AChR (163)

COX (137)

Dopamine Receptor (131)

Histamine Receptor (127)

DNA/RNA Synthesis (122)

HIV Protease (117)

Parasite (116)

Antifungal (105)

Sodium Channel (100)

Calcium Channel (95)

Potassium Channel (89)

VEGFR (85)

EGFR (78)

Topoisomerase (78)

PDE (76)

PI3K (67)

Reactive Oxygen Species (67)

P450 (61)

FLT (58)

Influenza Virus (58)

Ferroptosis (56)

Glucocorticoid Receptor (56)

PPAR (56)

CDK (55)

Dehydrogenase (54)

Estrogen/progestogen Receptor (54)

HCV Protease (54)

NF-κB (53)

PDGFR (53)

GABA Receptor (50)

SARS-CoV (50)

c-Kit (49)

Microtubule Associated (49)

HDAC (48)

FGFR (48)

JAK (48)

mTOR (42)

RAAS (42)

Prostaglandin Receptor (42)

Mitophagy (39)

c-Met/HGFR (39)

Estrogen Receptor/ERR (37)

Src (36)

HBV (36)

Nucleoside Antimetabolite/Analog (35)

Reverse Transcriptase (33)

Tyrosine Kinases (33)

Adenosine Receptor (32)

Serotonin Transporter (32)

iGluR (32)

Androgen Receptor (31)

HSV (31)

Bcr-Abl (31)

GPR (30)

Virus Protease (30)

Proteasome (30)

ribosome (30)

BTK (29)

TNF (28)

Norepinephrine (28)

Raf (28)

AChE (28)

MAO (27)

ATPase (26)

Opioid Receptor (26)

Progesterone Receptor (26)

PARP (25)

HER (25)

NMDAR (25)

GluR (25)

Akt (24)

TRP/TRPV Channel (24)

Proton pump (24)

Aurora Kinase (23)

Transferase (23)

Carbonic Anhydrase (23)

HSP (23)

Epigenetic Reader Domain (23)

ROS (23)

Phosphatase (23)

Antioxidant (22)

DNA Alkylator/Crosslinker (22)

Beta Amyloid (22)

p38 MAPK (22)

Antifection (22)

P-gp (22)

HIF/HIF Prolyl-Hydroxylase (22)

PKC (21)

MEK (21)

Monoamine Oxidase (20)

IL Receptor (20)

Antiviral (20)

Thrombin (19)

DPP-4 (19)

Drug Metabolite (18)

ERK (18)

Mitochondrial Metabolism (18)

ALK (18)

Phospholipase (18)

c-RET (18)

MMP (18)

Trk receptor (17)

AMPK (17)

Retinoid Receptor (17)

Interleukin (17)

c-Fms (16)

Histone Methyltransferase (16)

GSK-3 (16)

CXCR (16)

BCL (16)

Endothelin Receptor (16)

TLR (15)

Caspase (15)

NO Synthase (15)

E1/E2/E3 Enzyme (15)

TAM Receptor (15)

SGLT (15)

MRP (15)

STAT (14)

Gamma-secretase (14)

P2X Receptor (14)

Thyroid hormone receptor(THR) (14)

Antifolate (14)

CCR (13)

PKA (13)

Lipoxygenase (13)

CFTR (13)

Syk (13)

Chk (13)

S1P Receptor (13)

DNA-PK (13)

p53 (12)

DNA Alkylation (12)

LPL Receptor (12)

HIF (12)

NADPH (12)

DHFR (12)

HMG-CoA Reductase (12)

Nrf2 (12)

ROCK (12)

DNA gyrase (12)

Guanylate cyclase (11)

IGF-1R (11)

Amino Acids and Derivatives (11)

Integrin (11)

Wnt/beta-catenin (11)

Cannabinoid Receptor (11)

TGF-beta/Smad (11)

FAK (11)

Neurokinin receptor (11)

Hedgehog/Smoothened (11)

Factor Xa (11)

FXR (10)

Mdm2 (10)

P2Y Receptor (10)

Serine Protease (10)

Reductase (10)

Glutathione Peroxidase (10)

PLK (10)

CSF-1R (10)

Sigma receptor (9)

S6 Kinase (9)

DNA Methyltransferase (9)

NOS (9)

Vasopressin Receptor (9)

CETP (9)

Histone Demethylase (9)

Hydroxylase (9)

Indoleamine 2,3-Dioxygenase (IDO) (9)

CaMK (9)

Glucosidase (9)

IAP (9)

Chloride channel (9)

Kinesin (8)

CAT (8)

ABC (8)

ROS Kinase (8)

Ras (8)

Casein Kinase (8)

OX Receptor (8)

Leukotriene Receptor (8)

Tyrosinase (8)

ATM/ATR (8)

Smo (8)

JNK (8)

BACE (7)

Aminopeptidase (7)

DNA (7)

Sirtuin (7)

Aryl Hydrocarbon Receptor (7)

RSV (7)

Glucokinase (7)

Pim (7)

Xanthine Oxidase (7)

Beta-Secretase (7)

Monoamine Transporter (7)

LTR (6)

Fatty Acid Synthase (6)

Glucagon Receptor (6)

Isocitrate Dehydrogenase (IDH) (6)

AhR (6)

Cysteine Protease (6)

Imidazoline Receptor (6)

PAK (6)

RIP kinase (6)

Ligand for E3 Ligase (6)

Acyltransferase (6)

IκB/IKK (6)

ROR (6)

IRAK (6)

Tie-2 (5)

Anti-infection (5)

Lipid (5)

IDO (5)

PGE Synthase (5)

MT Receptor (5)

NOD (5)

cholecystokinin (5)

Serine/threonin kinase (5)

Liver X Receptor (5)

FAAH (5)

IFNAR (5)

Complement System (5)

Ephrin Receptor (5)

GlyT (5)

GPCR19 (5)

Melanocortin Receptor (4)

DprE1 (4)

Annexin A (4)

CGRP Receptor (4)

PD-1/PD-L1 (4)

UGT (4)

Decarboxylase (4)

Neuropeptide Y Receptor (4)

Gap Junction Protein (4)

CaSR (4)

Bradykinin Receptor (4)

Molecular Glues (4)

Acetyl-CoA Carboxylase (4)

KSP (4)

GNRH Receptor (4)

YAP (4)

LPA Receptor (4)

NADPH-oxidase (4)

Melatonin Receptor (4)

NOD-like Receptor (NLR) (4)

Neprilysin (4)

Wee1 (4)

MAPK (4)

GHSR (4)

CRFR (4)

GST (3)

Oxytocin Receptor (3)

Arginase (3)

CRM1 (3)

Aromatase (3)

PDK (3)

Adenosine deaminase (3)

Epoxide Hydrolase (3)

Myosin (3)

LDL (3)

Glutaminase (3)

Na-K-Cl cotransporter (3)

NAMPT (3)

Hexokinase (3)

Protease-activated Receptor (3)

Rho (3)

Free radical scavengers (3)

Somatostatin (3)

DUB (3)

Monocarboxylate transporter (3)

Telomerase (3)

TOPK (3)

STING (3)

Cell wall (3)

OAT (3)

advanced glycation end products (2)

PKM (2)

MLK (2)

Discoidin Domain Receptor (DDR) (2)

NEDD8 (2)

Aquaporin (2)

p97 (2)

GSNOR (2)

Taste receptor (2)

IRE1 (2)

Porcupine (2)

Ligands for Target Protein for PROTAC (2)

transporter (2)

Galectin (2)

VDA (2)

ATP Citrate Lyase (2)

BCRP (2)

Stearoyl-CoA Desaturase (SCD) (2)

Glutathione reductase (2)

PROTAC Linker (2)

PERK (2)

Lipase (2)

Integrase (2)

CD73 (2)

Histone Acetyltransferase (2)

PYK2 (2)

Thrombopoietin Receptor (2)

Phosphorylase (2)

GluCls (2)

PAI-1 (2)

FLAP (2)

Adenylyl cyclase (1)

PAD (1)

Angiotensin-converting Enzyme (ACE) (1)

Motilin Receptor (1)

PROTACs (1)

Adiponectin receptor (1)

VDAC (1)

Apelin receptor (1)

AAK1 (AP2 associated kinase 1) (1)

PAFR (1)

Stemness kinase (1)

Hck (1)

HCN Channel (1)

Fas/FasL (1)

Immunology/Inflammation related (1)

GRK (1)

Anion Exchanger (1)

ACK (1)

MTH1 (1)

GTPase (1)

N-Acetylglucosaminyltransferase (1)

MALT (1)

KLF (1)

PI4K (1)

Dynamin (1)

Na+/Ca2+ Exchanger (1)

Hippo pathway (1)

Methionine Adenosyltransferase (MAT) (1)

MELK (1)

DYRK (1)

Pyroptosis (1)

RXFP receptor (1)

ASK (1)

Hydrogenase (1)

cAMP (1)

SGK (1)

RAR/RXR (1)

NPC1L1 (1)

MNK (1)

Survivin (1)

Platelet aggregation (1)

OXPHOS (1)

LHRH (1)

CRISPR/Cas9 (1)

c-Myc (1)

BMI-1 (1)

Thioredoxin (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty