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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $681 | Backorder |
Description | Dentonin (AC-100) is a synthetic fragment derived from MEPE that enhances osteogenesis by promoting osteoprogenitor adhesion and facilitating the survival of immature adherent cells. It does not have a significant effect on mature osteoblasts. Dentonin is useful for research on phosphate homeostasis and bone metabolism. |
In vitro | MEPE, a secreted glycophosphoprotein belonging to the SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) family, plays a crucial role in regulating bone mass and osteoblast activity. Dentonin, at concentrations of 3-30 μg/ml over 2-24 hours, significantly enhances cell proliferation and promotes cell adhesion, though it does not affect the overall number of cells adhered. Additionally, Dentonin markedly increases osteoblast spreading, demonstrating significantly larger cell areas compared to other treatments. |
Alias | AC-100 |
Molecular Weight | 2538.625 |
Formula | C107H160N30O42 |
Cas No. | 400090-20-2 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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