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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Endotoxin Inhibitor TFA is a synthetic peptide that exhibits high-affinity binding to lipid A, effectively detoxifying LPS and impeding LPS-induced cytokine release in vivo. It also suppresses the febrile response to LPS while demonstrating minimal toxicity and lethality [1]. |
In vivo | The endotoxin inhibitor TFA, when administered intraperitoneally (i.p.) at a dose of 0.5 mg/kg, significantly reduces the heat exposure-induced increase in the mRNA levels of IL-1β, COX-2, IκB-β, and LPS activity. Additionally, it mitigates the hypothermia and plasma ACTH and catecholamine responses elicited by heat exposure in aged rats [1]. |
Molecular Weight | 1908.72 |
Formula | C67H103F18N15O24S2 |
Cas No. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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