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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | GrTx1, a peptide toxin derived from Grammostola rosea spider venom, selectively inhibits sodium channels Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6, and Nav1.7, with IC50 values of 0.63 µM, 0.23 µM, 0.77 µM, 1.29 µM, 0.63 µM, and 0.37 µM, respectively [2]. This compound has applications in neurological disease research [1]. |
In vitro | GrTx1 (0-100 μΜ, 3 minutes) effectively inhibits approximately 85% of the Na+ currents in neuroblastoma F-11 cells without affecting common K+ channels such as Kv1.1 and 1.4, demonstrating an IC50 value of 2.8 μM [1]. |
Molecular Weight | 3697.43 |
Formula | C159H243N45O41S8 |
Cas No. |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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