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Riluzole
🥰Excellent
Catalog No. T0349Cas No. 1744-22-5
Alias RP-54274, PK 26124
Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Riluzole
🥰Excellent
Purity: 99.88%
Catalog No. T0349Alias RP-54274, PK 26124Cas No. 1744-22-5
Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | 42 € | In Stock | |
| 100 mg | 55 € | In Stock | |
| 500 mg | 111 € | In Stock | |
| 1 g | 149 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 47 € | In Stock |
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Purity:99.88%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Riluzole (RP-54274) is a glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS. |
| Targets&IC50 | GABA:43 μM |
| In vitro | Riluzole readily crosses the blood-brain barrier. Treatment of rodents with transient cerebral ischemia with 8 mg/kg i.p. Riluzole completely inhibited the massive release of glutamic acid induced by local ischemia. |
| In vivo | Riluzole readily crosses the blood-brain barrier. Treatment of rodents with transient cerebral ischemia with 8 mg/kg i.p. Riluzole completely inhibited the massive release of glutamic acid induced by local ischemia. |
| Alias | RP-54274, PK 26124 |
| Molecular Weight | 234.2 |
| Formula | C8H5F3N2OS |
| Cas No. | 1744-22-5 |
| Smiles | NC1=NC2=C(S1)C=C(OC(F)(F)F)C=C2 |
| Relative Density. | 1.572 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/mL (256.19 mM)  H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: 43 mg/mL (183.6 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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