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Riluzole hydrochloride
🥰Excellent
Catalog No. T41265Cas No. 850608-87-6
Alias PK 26124 hydrochloride, AQST-117 hydrochloride
Riluzole hydrochloride (PK 26124 hydrochloride) is an anticonvulsant compound belonging to the family of sodium channel blockers that inhibits GABA uptake.Riluzole hydrochloride is a sodium-glutamate antagonist with anticancer and neuroprotective activity and can be used to study amyotrophic lateral sclerosis and neurological disorders.
Riluzole hydrochloride
🥰Excellent
Purity: 99.76%
Catalog No. T41265Alias PK 26124 hydrochloride, AQST-117 hydrochlorideCas No. 850608-87-6
Riluzole hydrochloride (PK 26124 hydrochloride) is an anticonvulsant compound belonging to the family of sodium channel blockers that inhibits GABA uptake.Riluzole hydrochloride is a sodium-glutamate antagonist with anticancer and neuroprotective activity and can be used to study amyotrophic lateral sclerosis and neurological disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $31 | In Stock | |
| 50 mg | $44 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $39 | In Stock |
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Purity:99.76%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Riluzole hydrochloride (PK 26124 hydrochloride) is an anticonvulsant compound belonging to the family of sodium channel blockers that inhibits GABA uptake.Riluzole hydrochloride is a sodium-glutamate antagonist with anticancer and neuroprotective activity and can be used to study amyotrophic lateral sclerosis and neurological disorders. |
| Targets&IC50 | GABA receptor:43 μM |
| In vitro | Riluzole hydrochloride (20-100 μM) significantly prolonged the decay of IPSCs, resulting in almost no change in the total charge transfer[1]. |
| In vivo | Riluzole hydrochloride (8 mg/kg;i.p.) can inhibit auditory and aversive emotional responses in adult rats with arthritis, but does not affect spinal withdrawal thresholds[2]. |
| Alias | PK 26124 hydrochloride, AQST-117 hydrochloride |
| Molecular Weight | 270.66 |
| Formula | C8H6ClF3N2OS |
| Cas No. | 850608-87-6 |
| Smiles | Cl.Nc1nc2ccc(OC(F)(F)F)cc2s1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (295.57 mM), Sonication is recommended. H2O: 2 mg/mL (7.39 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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