Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 347.00 | |
5 mg | In stock | $ 838.00 | |
10 mg | In stock | $ 1,160.00 | |
25 mg | In stock | $ 1,720.00 | |
50 mg | In stock | $ 2,320.00 | |
100 mg | In stock | $ 3,130.00 |
Description | Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist. |
In vitro | Human pancreatic polypeptide (hPP) is one such peptide, being released postprandially from F cells of the pancreatic islets depending on caloric load, food consumption and circadian rhythm. It is a C-terminally amidated 36 amino acid peptide with a characteristic hairpin-like pancreatic polypeptide (PP)-fold and acts at the Y4 receptor to induce satiety and delay gastric emptying and motility[1]. Addition of the human pancreatic polypeptide (hPP) (10 nM-1 μM) results in a significant, dose-dependent reduction in both basal and stimulated release. Human pancreatic polypeptide (hPP) can also inhibit basal and stimulated NPY release with a pharmacological profile suggesting a role for Y4 presynaptic receptors[2]. |
Molecular Weight | N/A |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pancreatic Polypeptide (human) acetate GPCR/G Protein Neuroscience Neuropeptide Y Receptor Pancreatic Polypeptide Pancreatic Polypeptide Acetate inhibitor inhibit