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Homocarnosine acetate

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Catalog No. T32098L

Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation

Homocarnosine acetate

Homocarnosine acetate

🥰Excellent
Purity: 99.52%
Catalog No. T32098L
Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation
Pack SizePriceAvailabilityQuantity
1 mg$52In Stock
2 mg$72In Stock
5 mg$111In Stock
10 mg$176In Stock
25 mg$352In Stock
50 mg$492In Stock
100 mg$696In Stock
200 mg$938In Stock
1 mL x 10 mM (in DMSO)$140In Stock
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Purity:99.52%
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Product Introduction

Bioactivity
Description
Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation
In vitro
Homocarnosine acetate possesses greater tolerance to degradation by serum carnosinase relative to Carnosine. Homocarnosine acetate is known to be exclusively present in brain and cerebrospinal fluid and acts as a neuroprotective agent in a broad range of disease conditions. Homocarnosine acetate exerts antioxidant activity and prevent DNA oxidative damage to a similar extent as Carnosine[1]. Homocarnosine acetate is composed of γ-aminobutyric acid (GABA) and histidine and has a similar structure to Carnosine, with the only difference being an extra carbon atom in GABA compared to that in β-alanine of carnosine[1].
Chemical Properties
Molecular Weight300.31
FormulaC12H20N4O5
SmilesCC(O)=O.O=C(O)[C@H](CC1=CNC=N1)NC(CCCN)=O
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (166.49 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3299 mL16.6495 mL33.2989 mL166.4946 mL
5 mM0.6660 mL3.3299 mL6.6598 mL33.2989 mL
10 mM0.3330 mL1.6649 mL3.3299 mL16.6495 mL
20 mM0.1665 mL0.8325 mL1.6649 mL8.3247 mL
50 mM0.0666 mL0.3330 mL0.6660 mL3.3299 mL
100 mM0.0333 mL0.1665 mL0.3330 mL1.6649 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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