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G3-C12 acetate shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | 45 € | In Stock | |
5 mg | 116 € | In Stock | |
10 mg | 173 € | In Stock | |
25 mg | 314 € | In Stock | |
50 mg | 452 € | In Stock | |
100 mg | 620 € | In Stock | |
200 mg | 843 € | In Stock |
Description | G3-C12 acetate shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM. |
Targets&IC50 | GAL3:(kd)88 nM |
In vitro | G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. |
Molecular Weight | 1819.03 |
Formula | C76H119N23O25S2 |
Smiles | CC(C)C(C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C1CCCN1C(=O)C(CS)NC(=O)C(CC(=O)O)NC(=O)C(CC2=CN=CN2)NC(=O)C(C(C)O)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C4CCCN4C(=O)CNC(=O)C(CS)NC(=O)C5CCCN5C(=O)C(C(C)O)NC(=O)C(CC(=O)N)NC(=O)C(C)N.CC(=O)O |
Relative Density. | no data available |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||
Solubility Information | DMSO: Insoluble H2O: 5 mM | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
H2O
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