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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $170 | 35 days | |
1 mg | $325 | 35 days | |
5 mg | $1,420 | 35 days |
Description | Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2] |
Alias | Z-AEVD-FMK, Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone |
Molecular Weight | 610.63 |
Formula | C28H39FN4O10 |
Cas No. | 1135688-47-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: 10 mg/mL |
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