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Mad1 (6-21) (TFA)

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Catalog No. T81885

Mad1 (6-21) TFA, a fragment encompassing amino acids 6 to 21 of the Mad1 protein, exhibits a strong affinity for the PAH2 domain of mammalian Sin3A with a dissociation constant (Kd) of approximately 29 nM [1].

Mad1 (6-21) (TFA)

Mad1 (6-21) (TFA)

😃Good
Catalog No. T81885
Mad1 (6-21) TFA, a fragment encompassing amino acids 6 to 21 of the Mad1 protein, exhibits a strong affinity for the PAH2 domain of mammalian Sin3A with a dissociation constant (Kd) of approximately 29 nM [1].
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Product Introduction

Bioactivity
Description
Mad1 (6-21) TFA, a fragment encompassing amino acids 6 to 21 of the Mad1 protein, exhibits a strong affinity for the PAH2 domain of mammalian Sin3A with a dissociation constant (Kd) of approximately 29 nM [1].
In vitro
The PAH2 domain of mSin3A forms a left-handed four-helix bundle with an up-and-down topology, where residues from all helices and intervening turns create a tightly organized domain that possesses a substantial hydrophobic core.
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Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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