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Melanostatin, frog

Name: Melanostatin, frog
Brand: TargetMol
SKU: TP2603
Rating: 4.5 (1 reviews)

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Catalog No. TP2603Cas No. 134709-16-3

Melanostatin, frog, is an inhibitor of α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM [1] [2].

Melanostatin, frog

😃Good

Catalog No. TP2603Cas No. 134709-16-3

Melanostatin, frog, is an inhibitor of α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM [1] [2].

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Product Introduction

Bioactivity

Description	Melanostatin, frog, is an inhibitor of α-melanocyte-stimulating hormone (α-MSH) release, with an IC50 of 60 nM [1] [2].
In vitro	Melanostatin, a frog compound at 1 μM concentration, enhances potassium current while reducing sodium and calcium currents, leading to hyperpolarization of the cell membrane [1].

Chemical Properties

Molecular Weight	4243.67
Formula	C₁₈₉H₂₈₅N₅₃O₅₇S
Cas No.	134709-16-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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