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TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating peptide demonstrates significant potential in biotechnological applications.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $135 | In Stock | |
2 mg | $198 | In Stock | |
5 mg | $312 | In Stock | |
10 mg | $467 | In Stock | |
25 mg | $767 | In Stock | |
50 mg | $1,070 | In Stock | |
100 mg | $1,450 | In Stock |
Description | TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating peptide demonstrates significant potential in biotechnological applications. |
In vitro | TAT (YGRKKRRQRRR), corresponding to amino acids 47-57 of the HIV-1 TAT protein, embodies the positively charged protein transduction domain (TAT-PTD) that efficiently permeates the plasma membrane of live cells. This characteristic is utilized for intracellular delivery of proteins, drugs, and genes. Owing to its TAT-PTD, TAT (YGRKKRRQRRR; TAT-PTD) can traverse the cell's hydrophobic lipid bilayer through passive diffusion[1]. |
Molecular Weight | 1559.83 |
Formula | C64H118N32O14 |
Cas No. | 191936-91-1 |
Smiles | [C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC1=CC=C(O)C=C1)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N |
Relative Density. | 1.54 g/cm3 (Predicted) |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O: Soluble |
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