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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype of G-protein coupled receptors involved in mediating thrombin's cellular effects. Exhibiting high specificity for PAR-1 over PAR-2, its selectivity was assessed via cell-based calcium signaling assays in HEK293 cells. As an agonist, it is instrumental for in vivo investigations of PAR-1 activation. PAR-1 also collaborates with PAR-4, influencing thrombin-induced hepatocellular carcinoma within 'coagulation type' tumor environments where thrombin generation occurs. |
Molecular Weight | 883.02 |
Formula | C42H63FN12O8 |
Cas No. | 211190-38-4 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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